Vitiligo
Vitiligo
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DOI：
10.1007/978-3-319-62960-5
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发表时间：
2019-11
期刊：
影响因子：
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通讯作者：
J. Seneschal;J. Mazereeuw-Hautier;A. Taïeb
中科院分区：
文献类型：
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作者：
J. Seneschal;J. Mazereeuw-Hautier;A. Taïeb
自从这本书的第一版出版以来，人们对白癜风有了新的认识。这一广泛修订和更新的第二版，由世界各地的专家在该领域编写，充分反映了这一进展。与其他常见的慢性皮肤病如银屑病和特应性皮炎相比，这种疾病的明显、简单和症状不佳的表现对其研究是一个很大的缺点。一个良好的皮肤为基础的攻击角度也缺乏，因为泛发性白癜风是明确的概括皮肤疾病的观点作为一个系统性的未知失调（素质）的简单目标。这种观点主要限制白癜风的自身免疫素质和皮肤事件的表现，这是很容易检测到使用皮肤活检在大多数其他情况下，还没有准确记录，与论点，临床诊断是足够的白癜风患者的管理。这丰富的说明第二版反映了不断的国际努力，分享有关这种疾病的临床，病理生理和治疗水平收集的信息。它的目的仍然是在临床和研究层面上弥合现有知识，指出许多未解决的问题，并描绘未来的研究重点。
Since the first edition of this book was published, new knowledge has been gained on Vitiligo. This widely revised and updated second edition, written by worldwide experts in the field, fully reflects this progress. The apparently, simple and poorly symptomatic presentation of the disease has been a strong disadvantage to its study, as compared to other common chronic skin disorders such as psoriasis and atopic dermatitis. A good skin-based angle of attack is also lacking because generalized Vitiligo is clearly epitomizing the view of skin diseases as simple targets of a systemic unknown dysregulation (diathesis). This view has mostly restricted Vitiligo to the manifestation of an auto-immune diathesis and skin events, which are easily detected using skin biopsies in most other situations, have not been precisely recorded, with the argument that a clinical diagnosis was sufficient for the management of the patient with Vitiligo. This richly illustrated second edition reflects the constant international effort to share the information gathered about this disorder at the clinical, pathophysiological and therapeutic levels. Its aim still being to bridge current knowledge at the clinical and investigative level, to point to the many unsolved issues, and to delineate future priorities for research.