FINE-STRUCTURE OF EYE OF A VISUAL MUTANT, A-TYPE, OF DROSOPHILA-MELANOGASTER
FINE-STRUCTURE OF EYE OF A VISUAL MUTANT, A-TYPE, OF DROSOPHILA-MELANOGASTER
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DOI：
10.1016/0022-1910(72)90109-6
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发表时间：
1972-01-01
影响因子：
2.2
通讯作者：
PERRY, MM
中科院分区：
文献类型：
--
作者：
COSENS, D;PERRY, MM
对果蝇视觉突变体（A型）眼睛超微结构的研究揭示了感光细胞内一些有趣的结构变化，这可能有助于将结构与功能联系起来。在羽化的突变眼似乎是结构正常的，除了小网膜细胞色素位于每个横纹肌后面的一段距离。在不同年龄检查的眼睛显示退行性变化只在横纹肌。在第5天，一些横纹肌显示出小面积的囊泡形成。在2周时，许多横纹肌的大小减小和/或被囊泡形成部分破坏，但在4周时，恶化没有广泛进展。野生型的眼睛没有这种随年龄的退化。这些发现进行了讨论，在感光细胞器中产生的各种代理异常。
A study of the ultrastructure of the eye of a visual mutant (A-type) ofDrosophilahas revealed some interesting structural changes within the photoreceptor cells which may help in relating structure to function. At eclosion the mutant eye appears to be structurally normal, with the exception that the retinula cell pigment lies at some distance behind each rhabdomere. Eyes examined at different ages show degenerative changes exclusively in the rhabdomeres. At 5 days a few of the rhabdomeres show small areas of vesiculation. At 2 weeks many of the rhabdomeres are reduced in size and/or are partially disrupted by vesiculation, yet at 4 weeks deterioration has not progressed extensively. Wildtype eyes show no such degeneration with age. The findings are discussed in relation to abnormalities produced in photoreceptor organelles by a variety of agents.