A preliminary comparative study of two treatment planning systems developed for boron neutron capture therapy: MacNCTPlan and SERA.
A preliminary comparative study of two treatment planning systems developed for boron neutron capture therapy: MacNCTPlan and SERA.
复制标题
针对硼中子俘获疗法开发的两种治疗计划系统：MacNCTPlan 和 SERA 的初步比较研究。
DOI：
10.1118/1.1485058
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发表时间：
2002
期刊：
影响因子：
3.8
通讯作者：
S. Green
中科院分区：
文献类型：
--
作者：
C. Wojnecki;S. Green
专门为BNCT开发了两个治疗计划系统：哈佛-麻省理工学院小组开发的MacNCTPlan和INEEL/蒙大拿州立大学小组开发的SERA系统。为了比较治疗计划系统计算的剂量分量，从而比较可用的临床结果，首先比较代码的基本特征是很重要的。本研究调查的重建技术和形式的横截面库所使用的两个治疗计划系统的热中子注量分布的影响。将0.0253 eV、1 keV、5 keV、10 keV、100 keV和1 MeV的六个单向中子源定向到充满水的简单几何模型上。通用蒙特卡罗辐射输运程序MCNP被用作本研究的参考工具。对于研究的例子，它被发现，用于几何表示（在MacNCTPlan）和横截面表示（在SERA）的方法被发现直接影响计算结果的准确性。
Two treatment planning systems have been specifically developed for BNCT: MacNCTPlan by the Harvard-MIT group and the SERA system developed by the INEEL/Montana State University group. In order to compare the dose components computed by the treatment planning systems, and therefore the clinical results available, it is important to first compare the basic features of the codes. This study investigated the effect of the reconstruction techniques and the form of the cross-section libraries used by the two treatment planning systems on the thermal neutron fluence distributions. Six mono-directional neutron sources of 0.0253 eV, 1 keV, 5 keV, 10 keV, 100 keV, and 1 MeV were directed onto simple geometric phantoms filled with water. The general-purpose Monte Carlo radiation transport code MCNP was used as a reference tool in this study. For the examples studied, it is found that the methods used for geometry representation (in MacNCTPlan) and for cross-section representation (in SERA) were found to impact directly on the accuracy of the calculated results.