Prevalence and clinical features of atypical depression in depressed outpatients: a 467-case study

Prevalence and clinical features of atypical depression in depressed outpatients: a 467-case study
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DOI:
10.1016/s0165-1781(99)00035-9
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发表时间:
1999-06-30
影响因子:
11.3
通讯作者:
Benazzi, F
Benazzi, F
中科院分区:
医学2区
文献类型:
--
作者:
Benazzi, F

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调查了467例门诊单、双相抑郁患者的DSM-IV不典型抑郁的患病率以及非典型抑郁与非典型抑郁的差异。采用符合DSM-IV标准的症状和病史综合评估、蒙哥马利-阿斯伯格抑郁评定量表和全球功能评估量表对连续出现严重抑郁发作的门诊患者进行评估。不典型抑郁患病率为38.1%。在调查的变量中(单相和双相诊断、发病年龄、性别、精神病、共病、慢性病、病程、复发和严重程度),发病年龄显著较低,女性、共病和双相II型障碍在不典型抑郁症中明显更常见。除发病年龄外,双相II型非典型抑郁症与单相非典型抑郁症之间的比较未显示出显著差异。研究结果表明,非典型抑郁症和非典型抑郁症在私人诊所门诊患者中存在重要的临床差异。(C)1999爱思唯尔爱尔兰科学有限公司。保留所有权利。
The prevalence of DSM-IV atypical depression and differences between atypical versus non-atypical depression were investigated in 467 unipolar and bipolar depressed outpatients in private practice. Consecutive outpatients presenting for treatment of a major depressive episode were assessed with the Comprehensive Assessment of Symptoms and History following DSM-IV criteria, the Montgomery-Asberg Depression Rating Scale, and the Global Assessment of Functioning Scale. The prevalence of atypical depression was 38.1%. Of the variables investigated (unipolar and bipolar diagnoses, age at onset, gender, psychosis, comorbidity, chronicity, duration of illness, recurrences, and severity), age at onset was significantly lower, and female gender, comorbidity, and bipolar II disorder were significantly more common in atypical than nonatypical depression. Comparisons between bipolar II atypical depression and unipolar atypical depression did not show significant differences, apart from age at onset. Findings suggest that there are important clinical differences between atypical and non-atypical depression in private practice outpatients. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.