SUBLETHAL MUSCLE-FIBER INJURIES AFTER HIGH-TENSION ANAEROBIC EXERCISE
SUBLETHAL MUSCLE-FIBER INJURIES AFTER HIGH-TENSION ANAEROBIC EXERCISE
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DOI：
10.1007/bf00635996
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发表时间：
1988-02-01
期刊：
影响因子：
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通讯作者：
EKBLOM, B
中科院分区：
文献类型：
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作者：
FRIDEN, J;SEGER, J;EKBLOM, B
本文研究了11名17-28岁男性优秀短跑运动员的股外侧肌，探讨了高张力无氧肌肉训练对肌纤维精细结构的影响。为了重现这种训练方案，6名受试者在跑步机上重复跑20次，每次25秒，中间间隔2分35秒，速度相当于他们个人200米最好成绩的86%。训练后约2小时的pas染色切片显示1型和2B型纤维糖原耗竭。在光镜下，未观察到炎症或纤维断裂的迹象。然而，在超微结构水平上，经常检测到收缩物质和细胞器的异常。z波段流化、自噬空泡和线粒体异常最为明显。没有进行常规剧烈运动的短跑运动员的对照标本也显示出结构偏差，尽管程度较轻。据推测，在短跑训练中，腿部肌肉组织承受巨大的机械和代谢压力，从而导致本文报道的退行性反应。
The vastus lateralis muscles of eleven male elite sprinters (17–28 years) were investigated in order to examine the impact of high tension anaerobic muscular work on muscle fibre fine structure. In an attempt to reproduce the training regimen six subjects ran 20 repetitions of 25 s on a treadmill with 2 min 35 s in between, at a speed corresponding to 86% of their personal best 200 m time. PAS-stained sections of biopsies taken approximately 2 h after training generally indicated glycogen depletion in type 1 and type 2B fibres. At the light microscopic level, no signs of inflammation or fibre rupture were observed. However, at the ultrastructural level, frequent abnormalities of the contractile material and the cytoplasmic organelles were detected. Z-band streaming, autophagic vacuoles and abnormal mitochondria were the most conspicuous observations. Control specimens from sprinters who did not perform the acute exercise routine also displayed structural deviations, although to a lesser degree. It is hypothesized that during sprint training the leg musculature is put under great mechanical and metabolic stress which causes the degenerative response reported here.