Radiofrequency lesioning for epileptogenic periventricular nodular heterotopia: A rational approach
Radiofrequency lesioning for epileptogenic periventricular nodular heterotopia: A rational approach
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DOI：
10.1111/j.1528-1167.2011.03116.x
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发表时间：
2011-09-01
期刊：
影响因子：
5.6
通讯作者：
Ebner, Alois
中科院分区：
文献类型：
--
作者：
Schmitt, Friedhelm C.;Voges, Juergen;Ebner, Alois
脑室周围结节性异位（PNHs）常与耐药癫痫有关。它们被认为是一个功能失调网络的一部分，与上面的皮层相连。因此，切除PNHs和额外的皮质切除术或肺叶切除术对于显著和持久的癫痫发作减少似乎是必不可少的。然而，这些手术有相当大的局限性，特别是在PNH附近有功能流利皮层的患者中。另外，立体定向神经外科可以减少手术创伤。本文报告一位56岁的男性患者，在立体定向引导下对孤立性PNH进行射频损伤后，癫痫不再发作。
Periventricular nodular heterotopias (PNHs) are frequently associated with pharmacoresistant epilepsy. They are considered part of a dysfunctional network, connected to the overlying cortex. Therefore, removal of the PNHs and additional cortectomy or lobectomy seem to be essential for significant and long-lasting seizure reduction. These procedures, however, can have considerable limitations, especially in patients with functional eloquent cortex adjacent to the PNH. Alternatively, stereotactic neurosurgery can reduce the surgical trauma. Presented is a 56-year-old man who became seizure-free after stereotactically guided radiofrequency lesioning of a solitary PNH.