Primary angiosarcoma arising in an angiomyolipoma of the kidney: case report and literature review.
Primary angiosarcoma arising in an angiomyolipoma of the kidney: case report and literature review.
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肾脏血管平滑肌脂肪瘤引起的原发性血管肉瘤：病例报告和文献综述
DOI：
10.1186/s13000-018-0730-z
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发表时间：
2018-08-16
影响因子：
2.6
通讯作者：
Wang H
中科院分区：
文献类型：
--
作者：
Guan H;Zhang L;Zhang Q;Qi W;Xie S;Hou J;Wang H
原发性肾脏血管肉瘤是一种少见的恶性肿瘤，具有侵袭性和血管分化。其预后是致命的，发病机制尚不清楚。肾血管平滑肌脂肪瘤是一种相对罕见的肾皮质肿瘤，是由不同比例的脂肪组织，梭形细胞，上皮样平滑肌细胞和异常厚壁血管。病例介绍在这里，我们报告了一个64岁的女性提出的主要投诉的一个渐进性扩大肿块在左腹部。腹部计算机断层扫描证实在左后肾筋膜中存在一个18 cm × 11 cm的肿瘤。显微镜检查和免疫组化染色证实血管平滑肌脂肪瘤和血管肉瘤的共存。此外，这两个组成部分相互穿插，它们之间有过渡带。ConclusionsIn这种情况下，我们首次描述了一个原发性肾血管肉瘤可能出现在预先存在的肾血管平滑肌脂肪瘤。
BackgroundPrimary angiosarcoma of the kidney is a rare and aggressive malignant tumor presenting with a recognizable vascular differentiation. Its prognosis is fatal and the pathogenesis remains unclear. Renal angiomyolipoma is a relatively infrequent renal cortical neoplasm and is composed of variable proportions of adipose tissue, spindle cells, epithelioid smooth muscle cells and abnormal thick-walled blood vessels.Case presentationHere, we reported a case in which a 64-year-old woman presenting with the chief complaint of a progressively enlarged mass in the left abdomen. Abdominal computed tomography confirmed presence of a tumor measuring 18 cm × 11 cm in the left posterior renal fascia. Microscopic examination and immunohistochemical staining confirmed co-existence of angiomyolipoma and angiosarcoma. Furthermore, the two components interspersed with each other and there were transitional zones between them.ConclusionsIn this case, we described for the first time a primary renal angiosarcoma possibly arising in a pre-existing angiomyolipoma of the kidney.
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影响因子：
6.2
作者：
Italiano, Antoine;Chen, Chun-Liang;Thomas, Rachael;Breen, Matthew;Bonnet, Francoise;Sevenet, Nicolas;Longy, Michel;Maki, Robert G.;Coindre, Jean-Michel;Antonescu, Cristina R.
通讯作者：
Antonescu, Cristina R.
影响因子：
2
作者：
Omiyale AO
通讯作者：
Omiyale AO
影响因子：
5.6
作者：
Meis-Kindblom, JM;Kindblom, LG
通讯作者：
Kindblom, LG
影响因子：
5.6
作者：
Trassard, M;LeDoussal, V;Coindre, JM
通讯作者：
Coindre, JM
影响因子：
3.3
作者：
Kenerson, Heidi;Fope, Andrew L.;Yeung, Raymond S.
通讯作者：
Yeung, Raymond S.