Osteoporosis of the slender smoker. Vertebral compression fractures and loss of metacarpal cortex in relation to postmenopausal cigarette smoking and lack of obesity.

Osteoporosis of the slender smoker. Vertebral compression fractures and loss of metacarpal cortex in relation to postmenopausal cigarette smoking and lack of obesity.
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苗条吸烟者的骨质疏松症。

DOI:
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发表时间:
1976
影响因子:
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通讯作者:
H. Daniell
H. Daniell
中科院分区:
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文献类型:
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作者:
H. Daniell

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一组38名年龄在70岁以下的因轻微创伤而发生椎体压缩性骨折的妇女中,绝经后吸烟的人数多于一组34名因严重创伤而发生骨折的妇女和一组572名其他妇女。65岁以前发生的晚期特发性骨质疏松症在非吸烟者中很少发现。研究人员测量了103名年龄在40至49岁之间的白人女性和208名年龄在60至69岁之间的白人女性第二掌骨中点的皮质面积百分比。在年轻一组中,肥胖者和非肥胖者、吸烟者和非吸烟者的骨骼没有数量上的差异。相比之下,在老年组中,绝经后吸烟者比不吸烟者表现出更多的骨质流失(P < 0.05)。非肥胖女性比肥胖女性骨质流失更多,这种差异在吸烟者中表现得最为明显。
A group of thirty-eight women under age 70 who sustained vertebral compression fractures during minor trauma included more postmenopausal smokers than a group of 34 similar women with fractures resulting from major trauma and more than a group of 572 other women. Advanced idiopathic osteoporosis occurring before age 65 was found rarely among nonsmokers. The percent cortical area at the second metacarpal midpoint was measured in 103 white women aged 40 to 49 years, and 208 white women aged 60 to 69 years. In the younger group, no quantitative differences were demonstrated between bones of the obese and the nonobese or between smokers and nonsmokers. In contrast, among the older group, postmenopausal smokers exhibited much more bone loss than did nonsmokers (P less than .001), and nonobese women demonstrated much more bone loss than did obese women, this difference being most striking among smokers.