Brilliant blue G selectively stains the internal limiting membrane/brilliant blue G-assisted membrane peeling
Brilliant blue G selectively stains the internal limiting membrane/brilliant blue G-assisted membrane peeling
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DOI：
10.1097/00006982-200607000-00007
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发表时间：
2006-07-01
影响因子：
3.3
通讯作者：
Ishibashi, Tatsuro
中科院分区：
文献类型：
--
作者：
Enaida, Hiroshi;Hisatomi, Toshio;Ishibashi, Tatsuro
目的：报告在黄斑裂孔 (MH) 和视网膜前膜 (ERM) 手术期间使用亮蓝 G (BBG) 染色内界膜 (ILM)。 方法：本研究被设计为介入性、非比较性、前瞻性临床病例系列。连续 20 名 MH 或 ERM 患者的 20 只眼睛接受了 BBG 辅助的 ILM 和 ERM 切除术。在 MH 病例中，产生玻璃体后脱离，然后将 0.25 mg/mL BBG 溶液注射到玻璃体腔中，并立即冲洗 BBG。这项技术改善了 ILM 的可视化，使剥离和手术能够成功进行。然而，在 ERM 情况下，在此浓度下无法确认 ERM 染色。最后，在所有情况下都删除了包括 ERM 在内的 ILM。术前和术后均进行眼科检查。结果：术后17例患者（85%）视力提高至少2个Snellen线。观察期间（平均随访+/- SD，7.3 +/- 1.0 个月）未观察到术后不良反应。结论：BBG 选择性对ILM 进行染色。正如这项短期研究所示，这项技术可以促进 MH 和 ERM 手术的管理，而不会产生任何副作用。
Purpose: To report the use of the dye brilliant blue G (BBG) for staining of the internal limiting membrane (ILM) during macular hole (MH) and epiretinal membrane (ERM) surgery.Methods: This study was designed as an interventional, noncomparative, prospective, clinical case series. Twenty eyes from 20 consecutive patients with MH or ERM underwent BBG-assisted ILM and ERM removal. In MH cases, a posterior vitreous detachment was created, followed by the injection of 0.25 mg/mL BBG solution into the vitreous cavity and immediate washout of the BBG. This technique improved visualization of the ILM, enabling peeling and surgery to be performed successfully. However, in ERM cases, staining of the ERM could not be confirmed at this concentration. Finally, the ILM including the ERM was removed in all cases. Preoperative and postoperative ophthalmic examinations were performed.Results: Postoperatively, 17 patients (85%) had visual acuity improved by at least 2 Snellen lines. No adverse effects were observed postoperatively during the observation period (mean follow-up +/- SD, 7.3 +/- 1.0 months).Conclusions: BBG selectively stains the ILM. This technique can facilitate the management of MH and ERM surgery without any adverse effects, as was shown in this short-term study.