Randomized controlled trial of a web-based computer-tailored smoking cessation program as a supplement to nicotine patch therapy
Randomized controlled trial of a web-based computer-tailored smoking cessation program as a supplement to nicotine patch therapy
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DOI：
10.1111/j.1360-0443.2005.01093.x
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发表时间：
2005-05-01
期刊：
影响因子：
6
通讯作者：
West, R
中科院分区：
文献类型：
--
作者：
Strecher, VJ;Shiffman, S;West, R
目的评估基于万维网的行为戒烟材料在尼古丁贴片使用者中的有效性。设计两组随机对照试验。在英格兰和爱尔兰设置万维网。参与者共3971名受试者，他们购买了特定品牌的尼古丁贴片并登录使用免费的基于网络的行为支持计划。干预基于网络的定制行为戒烟材料或基于网络的非定制材料。测量通过基于互联网的调查评估28天的连续戒烟率在6周的随访期和12周的10周的连续率随访。使用三种方法分析6周和12周的结果，在临床和统计上，定制条件下的参与者报告的持续禁酒率显著高于非定制条件下的参与者。在我们的初步分析中，所有登录治疗地点至少一次的受试者在定制条件下6周的持续戒断率分别为29.0%和23.9%(OR=1.3；P=0.0006)；在12周时持续戒断率分别为22.8%和18.1%(OR=1.3；P=0.0006)。结论本研究结果表明，基于网络的行为支持材料与尼古丁替代疗法联合使用是一种有益的方法。与基于网络的非定制戒烟计划相比，基于网络的计划从用户那里收集相关信息并根据他们的特定需求定制干预措施具有显著的优势。
Aim To assess the efficacy of World Wide Web-based tailored behavioral smoking cessation materials among nicotine patch users.Design Two-group randomized controlled trial.Setting World Wide Web in England and Republic of Ireland.Participants A total of 3971 subjects who purchased a particular brand of nicotine patch and logged-on to use a free web-based behavioral support program.Intervention Web-based tailored behavioral smoking cessation materials or web-based non-tailored materials.Measurements Twenty-eight-day continuous abstinence rates were assessed by internet-based survey at 6-week follow-up and 10-week continuous rates at 12-week follow-up.Findings Using three approaches to the analyses of 6- and 12-week outcomes, participants in the tailored condition reported clinically and statistically significantly higher continuous abstinence rates than participants in the non-tailored condition. In our primary analyses using as a denominator all subjects who logged-on to the treatment site at least once, continuous abstinence rates at 6 weeks were 29.0% in the tailored condition versus 23.9% in the non-tailored condition (OR = 1.30; P = 0.0006); at 12 weeks continuous abstinence rates were 22.8% versus 18.1%, respectively (OR = 1.34; P = 0.0006). Moreover, satisfaction with the program was significantly higher in the tailored than in the non-tailored condition.Conclusions The results of this study demonstrate a benefit of the web-based tailored behavioral support materials used in conjunction with nicotine replacement therapy. A web-based program that collects relevant information from users and tailors the intervention to their specific needs had significant advantages over a web-based non-tailored cessation program.