Polysomnographic and actigraphic evidence of sleep fragmentation in patients with irritable bowel syndrome
Polysomnographic and actigraphic evidence of sleep fragmentation in patients with irritable bowel syndrome
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DOI：
10.1093/sleep/26.6.747
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发表时间：
2003-09-15
期刊：
影响因子：
5.6
通讯作者：
Tarasiuk, A
中科院分区：
文献类型：
--
作者：
Rotem, AY;Sperber, AD;Tarasiuk, A
研究目的：描述肠易激综合征（IBS）患者的睡眠功能和质量。设计：一项具有历史对照组的前瞻性研究。设置：一家地区医院，也作为三级转诊中心。患者：18名IBS患者和20名轻度良性打鼾的匹配成人对照组。干预：多导睡眠图研究和腕动图研究。测量：所有受试者均接受睡眠研究并完成自我报告问卷（IBS严重程度、心理社会变量、睡眠功能和埃普沃思嗜睡量表）。结果：IBS患者的慢波期睡眠减少了70%以上（4.5 +/-7.3%vs 19.3 +/- 12.9%，P= 0.006），而第2期睡眠增加了（72.2 +/-6.6%vs 60.1 +/- 16.8%，P=0.01）。IBS组有明显的睡眠碎片，觉醒和觉醒指数显著高于IBS组（P
Study Objective: To characterize the function and quality of sleep in patients with irritable bowel syndrome (IBS).Design: A prospective study with a historic comparison group.Setting: A regional hospital that also serves as a tertiary referral center.Patients: Eighteen patients with IBS and a comparison group of 20 matched adults with mild benign snoring.Interventions: A polysomnography study and a wrist actigraphy study.Measurements: All subjects underwent sleep studies and completed self-report questionnaires (IBS severity, psychosocial variables, sleep function, and Epworth Sleepiness Scale). Fourteen IBS and 11 comparison patients underwent actigraphy.Results: The IBS patients had more than 70% less slow-wave stage sleep (4.5 +/- 7.3% vs 19.3 +/- 12.9%; P=0,006), compensated by increased stage 2 sleep(72.2 +/- 6.6% vs 60.1 +/- 16.8%; P=0.01). The IBS group had significant sleep fragmentation with a significantly higher arousal and awakening index (P