The anatomy of auditory word processing: Individual variability
The anatomy of auditory word processing: Individual variability
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DOI：
10.1006/brln.2000.2444
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发表时间：
2001-04-01
影响因子：
2.5
通讯作者：
Small, SL
中科院分区：
文献类型：
--
作者：
Burton, MW;Noll, DC;Small, SL
这项研究使用功能性磁共振成像（fMRI）来研究单个单词处理背后的神经基质，比较受试者之间和个体内部的激活模式。在单词重复任务中，受试者大声重复单个单词，并指示他们不要移动下巴。在一个涉及反向语音的控制条件下，受试者听到一个数字反向语音标记，并大声说出“犯罪”这个词。FMRI的平均结果显示，左侧后颞区和额叶下区以及辅助运动区被激活，与之前的PET研究相似。然而，个体受试者的数据显示，颞叶和额叶激活的位置存在差异。尽管这些结果支持了先前的影像学研究，表明听觉文字处理在颞后上回（STG）中平均定位，但它们更符合传统的神经心理学数据，即典型的颞后上回定位和实质性的个体差异。通过仔细使用头部约束和运动分析和校正方法，本研究进一步证明了在fMRI实验中使用显性发音的可行性，(C) 2001学术出版社。
This study used functional magnetic resonance imaging (fMRI) to investigate the neural substrate underlying the processing of single words, comparing activation patterns across subjects and within individuals. In a word repetition task, subjects repeated single words aloud with instructions not to move their jaws, In a control condition involving reverse speech, subjects heard a digitally reversed speech token and said aloud the word "crime." The averaged FMRI results showed activation in the left posterior temporal and inferior frontal regions and in the supplementary motor area, similar to previous PET studies. However, the individual subject data revealed variability in the location of the temporal and frontal activation. Although these results support previous imaging studies, demonstrating an averaged localization of auditory word processing in the posterior superior temporal gyrus (STG), they are more consistent with traditional neuropsychological data, which suggest both a typical posterior STG localization and substantial individual variability. By using careful head restraint and movement analysis and correction methods, the present study further demonstrates the feasibility of using overt articulation in fMRI experiments, (C) 2001 Academic Press.