A sulfated address for lymphocyte homing

A sulfated address for lymphocyte homing
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淋巴细胞归巢的硫酸化地址

DOI:
10.1038/ni1105-1067
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发表时间:
2005
期刊:
影响因子:
30.5
通讯作者:
R. McEver
R. McEver
中科院分区:
医学1区
文献类型:
--
作者:
R. McEver

文献摘要

被引文献

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由淋巴细胞表达的L-选择素与内皮上的特化聚糖相互作用以介导淋巴细胞滚动。两种磺基转移酶协同作用,将硫酸酯添加到聚糖上的特定糖残基上,这对该过程至关重要。
L-selectin expressed by lymphocytes interacts with specialized glycans on endothelium to mediate lymphocyte rolling. Two sulfotransferases that act cooperatively to add sulfate esters to a specific sugar residue on glycans are critical for this process.