PROPRIOCEPTIVE MODULATION OF SOMATOSENSORY EVOKED-POTENTIALS DURING ACTIVE OR PASSIVE FINGER MOVEMENTS IN MAN
PROPRIOCEPTIVE MODULATION OF SOMATOSENSORY EVOKED-POTENTIALS DURING ACTIVE OR PASSIVE FINGER MOVEMENTS IN MAN
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DOI：
10.1136/jnnp.44.10.942
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发表时间：
1981-01-01
影响因子：
11
通讯作者：
ABBRUZZESE, M
中科院分区：
文献类型：
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作者：
ABBRUZZESE, G;RATTO, S;ABBRUZZESE, M
在15名健康志愿者中，观察了主动和被动手指运动对刺激腕部正中神经或第Ⅰ指诱发的体感电位（SEP）的影响。与静息状态相比，受刺激手指的主动和被动运动均引起初级脑反应（N20-P25复合体）和N17 SEP分量的幅度显著降低，N17 SEP分量被认为反映了丘脑-皮层辐射的活性。以下脑SEP成分，在刺激后100 ms内，也被抑制在运动活动。无论是N11或N13成分的颈椎反应，反映背柱和背柱核的激活，分别进行修改。缺血性阻滞或大I组传入纤维从手后，主动或被动运动引起的SEP变化是不存在的，这表明在运动过程中由这样的外周传入产生的反馈的相关性。在主动和被动手指运动过程中，外周感受器（可能是肌梭末梢）的激活可能在皮层和皮层下（丘脑）水平诱导门控效应，这可能选择性地调节不同的感觉输入到皮层。
The effects of active and passive finger movements on somatosensory potentials [SEP] evoked by stimulation of the median nerve at the wrist or of finger I were investigated in 15 healthy human volunteers. Compared to the resting condition, both active and passive movements of the stimulated hand fingers induced a marked reduction in the amplitude of the primary cerebral response (N20-P25 complex) and of the N17 SEP component, which is supposed to reflect the activity of the thalamo-cortical radiation. The following cerebral SEP components, within 100 ms after the stimulus, were also depressed during motor activity. Neither N11 nor N13 components of the cervical response, reflecting the activation of dorsal columns and dorsal column nuclei respectively, were modified. The SEP changes induced by active or passive movements were absent after ischemic block or large group I afferent fibers from the hand, suggesting the relevance of the feedback generated by such peripheral afferents during movement. The activation of peripheral receptors (probably muscle spindle endings) during both active and passive finger movement probably induces a gating effect at both cortical and subcortical (thalamic) level, which might selectively modulate the different sensory inputs to the cortex.