Vagus nerve stimulation for bilateral temporal lobe epilepsy caused by fractionated radiation therapy: A case report
Vagus nerve stimulation for bilateral temporal lobe epilepsy caused by fractionated radiation therapy: A case report
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迷走神经刺激治疗分割放射治疗引起的双侧颞叶癫痫：一例报告
DOI：
10.1016/j.inat.2021.101429
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Inoue Tooru
中科院分区：
文献类型：
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作者：
Matsuo Yoko;Tanaka Hideaki;Morishita Takashi;Enatsu Rei;Inoue Tooru
背景：内侧颞叶癫痫（MTLE）是一种以颞叶为癫痫灶的疾病，通常涉及婴儿“初始诱发事件”史。病例描述我们描述了一个罕见的病例辐射引起的双侧MTLE。一位38岁的女性在7岁时接受了颅底胶质瘤的分割放疗。随后，她出现了耐药性癫痫发作。根据体征符合学、图像检查和脑电图，诊断为双侧MTLE伴左海马硬化伴双侧癫痫灶。她接受了迷走神经刺激（VNS）手术，这改善了她的癫痫发作；具体来说，她的掉落攻击完全停止了。结论据我们所知，这是第一例放射性诱导的双侧MTLE伴左海马硬化的病例。对于某些双侧MTLE病例，VNS被认为是一种很好的手术治疗方法。
BackgroundMesial temporal lobe epilepsy (MTLE) is a disorder with an epileptogenic focus within the temporal lobe that generally involves a history of infantile “initial precipitating incidents.”Case descriptionWe describe a rare case of radiation-induced bilateral MTLE. A 38-year-old woman underwent fractionated radiation therapy for tectal glioma at the age of 7 years. Subsequently, she experienced drug-resistant epileptic seizures. Based on the ictal semiology, image inspection, and electroencephalography, she was diagnosed with bilateral MTLE with left hippocampal sclerosis involving bilateral seizure foci. She underwent vagus nerve stimulation (VNS) surgery, which improved her seizures; specifically, her drop attacks completely stopped.ConclusionsTo our knowledge, this is the first reported case of radiation-induced bilateral MTLE with left hippocampal sclerosis. VNS is considered as a good surgical treatment for certain cases of bilateral MTLE cases.