Self-reported dry eye disease across refractive modalities.
Self-reported dry eye disease across refractive modalities.
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DOI：
10.1167/iovs.04-1294
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发表时间：
2005-06
影响因子：
4.4
通讯作者：
J. Nichols;C. Ziegler;G. Mitchell;K. Nichols
中科院分区：
文献类型：
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作者：
J. Nichols;C. Ziegler;G. Mitchell;K. Nichols
目的比较隐形眼镜佩戴者、眼镜佩戴者和临床患者（即不需要屈光矫正者）自我报告的干眼病。方法调查包括两个症状问题（干眼和光敏感），在一天的三个时间（上午、下午和晚上）询问频率和强度，以及一个自我感知问题（即：你认为你有眼睛干涩吗？）然后对干眼症和光敏感性量表进行计算、总结和评分，得出干眼症的分类。采用Logistic回归（二元和多项）和协方差分析来检验屈光矫正方式与干眼状态、症状发生频率和症状强度的日变化之间的关系。结果：总共完成了893次调查，样本中干眼的年龄调整频率为28.7%，其中3.5%的样本报告严重症状（两种症状至少为5级中的4级）。报告干眼病的最常见人群是隐形眼镜佩戴者（52.3%），其次是眼镜佩戴者（23.9%）和临床眼病患者（7.1%）。对年龄和性别进行校正后发现，隐形眼镜（校正优势比= 12.37,95%可信区间= 7.55-20.26）和眼镜佩戴者（校正优势比= 2.06,95%可信区间= 1.12-3.80）比普通眼镜佩戴者更容易报告干眼症。在调整了年龄和性别后，隐形眼镜佩戴者更有可能出现频繁的症状，并且在一天中症状增加（F = 51.4, P < 0.0001）。结论自述干眼症发生率较高，尤其是隐形眼镜佩戴者。
PURPOSE To compare self-reported dry eye disease across contact lens wearers, spectacles wearers, and clinical emmetropes (i.e., those not requiring refractive correction). METHODS The survey included two symptom questions (dryness and light sensitivity) that inquired about frequency and intensity at three times of day (morning, afternoon, and evening) and a self-perception question (i.e., Do you think you have dry eyes?). Dryness and light sensitivity scales were then calculated, summed, and scored, providing a dry eye classification. Logistic regression (binary and multinomial) and analysis of covariance were used to examine the relation between mode of refractive correction and dry eye status, frequency of symptoms, and diurnal change in symptom intensity. RESULTS Overall, 893 surveys were completed, and the age-adjusted frequency of dry eye in the sample was 28.7%, with 3.5% of the sample reporting severe symptoms (at least grade 4 of a possible 5 for both symptoms). Contact lens wearers were most likely to report dry eye disease (52.3%), followed by spectacle wearers (23.9%) and clinical emmetropes (7.1%). Adjustment for age and gender showed that contact lens (adjusted odds ratio = 12.37, 95% confidence interval = 7.55-20.26) and spectacle wearers (adjusted odds ratio = 2.06, 95% confidence interval = 1.12-3.80) were more likely than emmetropes to report dry eye problems. After adjustment for age and gender, contact lens wearers were shown to be more likely to experience frequent symptoms and an increase in symptoms throughout the day (F = 51.4, P < 0.0001). CONCLUSIONS The frequency of self-reported dry eye is high, especially in contact lens wearers.