Sex differences in whole body skeletal muscle mass measured by magnetic resonance imaging and its distribution in young Japanese adults
Sex differences in whole body skeletal muscle mass measured by magnetic resonance imaging and its distribution in young Japanese adults
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DOI：
10.1136/bjsm.37.5.436
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发表时间：
2003-10-01
影响因子：
18.4
通讯作者：
Fukunaga, T
中科院分区：
文献类型：
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作者：
Abe, T;Kearns, CF;Fukunaga, T
目的：利用连续的全身磁共振成像(MRI)数据，确定局部和总骨骼肌(SM)分布的性别差异，并探讨无脂肪质量(FFM)与总和局部SM的关系。方法：20名日本大学生(女10名，男10名)自愿参加这项研究。FFM采用双室密度法测量。全身MRI图像用1.5T扫描仪进行处理。从第一颈椎到踝关节获得连续的横断面图像，层厚1.0 cm。所有的MRI扫描被分成四个部分(SM、皮下脂肪组织、骨和残留组织)。在每个切片中，SM组织横截面积(CSA)被数字化，肌肉CSA乘以切片厚度计算出每个切片的肌肉组织体积。SM体积单位(升)乘以SM假定的恒定密度(1.041 mg/ml)，换算成质量单位(Kg)。结果：SM在连续的全身切片上的分布模式(曲线形状)男女基本相似，有两个大峰和三个小峰(手臂除外)。然而，女性的最大峰值出现在大腿上部，男性的峰值出现在肩膀水平。男性的体型更大(p
Objectives: To determine sex differences in the distribution of regional and total skeletal muscle (SM) using contiguous whole body magnetic resonance imaging (MRI) data, and to examine the relations between fat free mass (FFM) and total and regional SM masses.Methods: A total of 20 Japanese college students (10 women and 10 men) volunteered for the study. FFM was measured by two compartment densitometry. Whole body MRI images were prepared using a 1.5 T scanner. Contiguous transverse images with 1.0 cm slice thickness were obtained from the first cervical vertebra to the ankle joints. All MRI scans were segmented into four components ( SM, subcutaneous adipose tissue, bone, and residual tissues). In each slice, the SM tissue cross sectional areas (CSAs) were digitised, and the muscle tissue volume per slice was calculated by multiplying muscle CSA by slice thickness. SM volume units (litres) were converted into mass units (kg) by multiplying the volumes by the assumed constant density (1.041 mg/ml) for SM.Results: The SM distribution pattern (shape of curve) from the contiguous whole body slices was essentially similar for the two sexes, with two large peaks and three smaller peaks (arms excluded). However, the largest peak was observed at the upper portion of the thigh for women and at the level of the shoulder for men. Men had larger (p