Chronotropic incompetence and autonomic dysfunction in patients without structural heart disease
Chronotropic incompetence and autonomic dysfunction in patients without structural heart disease
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DOI：
10.1093/europace/eup433
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发表时间：
2010-04-01
期刊：
影响因子：
6.1
通讯作者：
Sugihara, Hiroki
中科院分区：
文献类型：
--
作者：
Kawasaki, Tatsuya;Kaimoto, Satoshi;Sugihara, Hiroki
运动引起的心率反应减弱，称为变时性功能不全（CI），已被报道为心血管死亡率的独立预测因子。我们研究了自主神经功能的变化，在运动测试和相关的结果与CI。方法和结果使用自行车测力计进行运动测试，在172例没有心脏病的证据。变时性功能不全定义为未能达到年龄预测的最大心率的85%，心率储备
Aims An attenuated heart rate response to exercise, termed chronotropic incompetence (CI), has been reported to be an independent predictor of cardiovascular mortality. We examined the change in autonomic function during exercise testing and correlated the results with CI.Methods and results Exercise testing using a bicycle ergometer was performed in 172 patients who had no evidence of cardiac disease. Chronotropic incompetence was defined as the failure to achieve 85% of the age-predicted maximum heart rate, heart rate reserve