Diagnostic performance of MR imaging findings and quantitative values in the differentiation of seromucinous borderline tumour from endometriosis-related malignant ovarian tumour
Diagnostic performance of MR imaging findings and quantitative values in the differentiation of seromucinous borderline tumour from endometriosis-related malignant ovarian tumour
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DOI：
10.1007/s00330-016-4533-x
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发表时间：
2017-04-01
影响因子：
5.9
通讯作者：
Togashi, Kaori
中科院分区：
文献类型：
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作者：
Kurata, Yasuhisa;Kido, Aki;Togashi, Kaori
为了评价定量值和MRI表现对血清粘液性交界性肿瘤（SMBTs）和卵巢癌相关恶性肿瘤（MT）的鉴别诊断性能，本回顾性研究检查了19个SMBTs和84个MT病灶。使用受试者操作特征分析评价以下定量值：总体和固体部分大小、液体信号强度（SI）、对比增强程度以及固体部分的平均和最小表观扩散系数（ADC）值。两名放射科医生独立评价了SMBT的四种MRI表现特征，T1加权图像上的液体SI和弥散加权图像上的固体部分SI。对SMBT的诊断，实性部分的平均ADC值显示最大的曲线下面积（0.860）（临界值：1.31 x 10（-3）mm（2）/s，敏感性：1.00，特异性：0.61）。T2加权像（T2 WI）高SI实性部分是最有用的发现，具有高特异性和观察者间的一致性（敏感性，0.58;特异性，0.95-0.96，kappa = 0.96），其次是T2 WI低SI核心（灵敏度0.48-0.63;特异性，0.98，kappa = 0.68）。实性部分，T2 WI高SI实性部分，T2 WI低SI核心区有助于鉴别SMBT和MT。SMBT是一种新分类的卵巢肿瘤，常与子宫内膜异位症相关。结果表明，ADC值与MRI表现的相关性很强，ADC值与MRI表现的相关性很强，ADC值与MRI表现的相关性很强，ADC值与MRI表现的相关性很强。“T2 WI高SI实性部分”是最有用的MRI表现。
To evaluate the diagnostic performance of quantitative values and MRI findings for differentiating seromucinous borderline tumours (SMBTs) from endometriosis-related malignant ovarian tumours (MT).This retrospective study examined 19 lesions from SMBT and 84 lesions from MT. The following quantitative values were evaluated using receiver-operating characteristic analysis: overall and solid portion sizes, fluid signal intensity (SI), degree of contrast-enhancement, and mean and minimum apparent diffusion coefficient (ADC) values of the solid portion. Two radiologists independently evaluated four MRI findings characteristic of SMBT, fluid SI on the T1-weighted image and SI of the solid portion on diffusion-weighted image. The diagnostic values of these findings and interobserver agreement were assessed.For diagnosing SMBT, the mean ADC value of the solid portion showed the greatest area under the curve (0.860) (cut-off value: 1.31 x 10(-3) mm(2)/s, sensitivity: 1.00, specificity: 0.61). The T2-weighted image (T2WI) high SI solid portion was the most useful finding, with high specificity and interobserver agreement (sensitivity, 0.58; specificity, 0.95-0.96, kappa = 0.96), followed by T2WI low SI core (sensitivity, 0.48-0.63; specificity, 0.98, kappa = 0.68).Mean ADC values of the solid portion, T2WI high SI solid portion, and T2WI low SI core were useful for differentiating SMBT from MT.SMBT is a newly categorised ovarian tumour often associated with endometriosis.Differentiation of SMBT from endometriosis-related malignant ovarian tumour is clinically important.Diagnostic performances of quantitative values and MRI findings were evaluated.Mean ADC value of the solid portion was the most useful value."T2WI high SI solid portion" was the most useful MRI finding.