A comparison of the ganglioside distributions of fat tissues in various animals by two-dimensional thin layer chromatography
A comparison of the ganglioside distributions of fat tissues in various animals by two-dimensional thin layer chromatography
复制标题
二维薄层色谱法比较不同动物脂肪组织中神经节苷脂的分布
作者：
M. Ohashi
采用二维薄层色谱法比较了人、兔、大鼠、小鼠、鸡和蛙的脂肪组织中神经节苷脂的分布。研究发现，神经节苷脂的分布存在着显著的物种差异，特别是在复合神经节苷脂的组成和相对浓度方面。与猪的脂肪组织不同，人、兔、大鼠、小鼠和鸡的脂肪组织中GM3是最丰富的神经节苷脂，而不是青蛙的脂肪组织。人类、家兔和鸡的数据显示仅NeuActype神经节苷脂的简单分布，而大鼠和小鼠的数据显示包含NeuAc型和neugc型神经节苷脂的复杂分布。青蛙脂肪体的神经节脂苷模式与哺乳动物脂肪组织明显不同，因为存在三种不同的、不寻常的单唾液神经节脂苷作为主要成分。在其他方面，在所有动物脂肪组织中普遍发现大量的二甲酰基神经节苷脂。
The ganglioside distributions of various fat tissues from human, rabbit, rat, mouse, chicken and frog were compared with pig adipose gangliosides by two-dimensional thin layers chromatography. It was found that there is a remarkable species variation in ganglioside distribution, especially in the composition and relative concentration of complex gangliosides. Differing from pig adipose tissues, those of human, rabbit, rat, mouse, chicken, but not frog, contained GM3 as a most abundant ganglioside. The data for human, rabbit and chicken indicated a simple distribution of only NeuActype gangliosides, while those for rat and mouse indicated a rather complicated pattern containing both NeuAc- and NeuGc-type gangliosides. The ganglioside pattern of the frog fat body differed markedly from those of mammalian fat tissues because of the presence of three different, unsual monosialosylgangliosides as major components. In other respects, a substantial amount of disialosylgangliosides was commonly found in all animal fat tissues.