Increased Eating Frequency Is Associated with Lower Obesity Risk, But Higher Energy Intake in Adults: A Meta-Analysis.
Increased Eating Frequency Is Associated with Lower Obesity Risk, But Higher Energy Intake in Adults: A Meta-Analysis.
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增加饮食频率与降低肥胖风险相关，但成人能量摄入量较高：荟萃分析
DOI：
10.3390/ijerph13060603
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发表时间：
2016-06-17
影响因子：
--
通讯作者：
Chen GX
中科院分区：
文献类型：
--
作者：
Wang YQ;Zhang YQ;Zhang F;Zhang YW;Li R;Chen GX
体重是由能量摄入来调节的，人类每天摄入能量数次。在这项荟萃分析中，我们评估了进食频率（EF）是否与没有任何饮食限制的成年人的肥胖风险和能量摄入有关。2015年7月之前发表的实验性和观察性研究是通过在多个数据库中进行英文文献检索来选择的。这些研究报告了EF和肥胖风险之间的关联（比值比，OR）在成年人谁没有在饮食限制。使用R软件进行统计分析。本分析包括10项横断面研究，包括65，742名参与者。以OR作为EF对肥胖风险影响的效应量。结果显示，EF的增加与肥胖几率降低0.83倍相关（即，OR = 0.83，95%置信区间（CI）0.70-0.99，p = 0.040）。关于EF对参与者能量摄入差异的影响的分析显示，EF增加与较高的能量摄入相关（β = 125.36，95%CI 21.76-228.97，p = 0.017）。我们的结论是，增加EF可能会导致较低的肥胖风险，但更高的能量摄入。临床试验是必要的，以确认这些结果，并评估临床实践的适用性。
Body weight is regulated by energy intake which occurs several times a day in humans. In this meta-analysis, we evaluated whether eating frequency (EF) is associated with obesity risk and energy intake in adults without any dietary restriction. Experimental and observational studies published before July 2015 were selected through English-language literature searches in several databases. These studies reported the association between EF and obesity risk (odd ratios, ORs) in adults who were not in dietary restriction. R software was used to perform statistical analyses. Ten cross-sectional studies, consisting of 65,742 participants, were included in this analysis. ORs were considered as effect size for the analysis about the effect of EF on obesity risk. Results showed that the increase of EF was associated with 0.83 time lower odds of obesity (i.e., OR = 0.83, 95% confidence intervals (CI) 0.70–0.99, p = 0.040). Analysis about the effect of EF on differences in participants’ energy intake revealed that increased EF was associated with higher energy intake (β = 125.36, 95% CI 21.76–228.97, p = 0.017). We conclude that increased EF may lead to lower obesity risk but higher energy intake. Clinical trials are warranted to confirm these results and to assess the clinical practice applicability.