Electrophoretic Mobilities of PEGylated Gold NPs
Electrophoretic Mobilities of PEGylated Gold NPs
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DOI：
10.1021/ja1049093
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发表时间：
2010-11-10
影响因子：
15
通讯作者：
Burda, Clemens
中科院分区：
文献类型：
--
作者：
Doane, Tennyson L.;Cheng, Yu;Burda, Clemens
纳米粒子的电迁移与许多技术和生物应用有关。我们将实验观察到的Au NP的电迁移与一个封闭形式的理论模型相关联，该模型描述了NP的关键特性，包括先前未知的Au NP核心zeta电位值、PEG电晕渗透率和颗粒-水凝胶摩擦系数。更一般地说，该理论阐明了在复杂环境中NP电迁移的新认识，建立了一个强大的和预测性的模型，以指导功能化NP的设计和表征。
Electromigration of nanoparticles (NPs) is relevant to many technological and biological applications. We correlate the experimentally observed electromigration of Au NPs with a closed-form theoretical model that furnishes key NP characteristics, including the previously unknown values of Au NP core zeta-potential, PEG-corona permeability, and particle-hydrogel friction coefficient. More generally, the theory furnishes new understanding of NP electromigration in complex environments, establishing a robust and predictive model to guide the design and characterization of functionalized NPs.