ACTOR - Aggregated Computational Toxicology Resource

ACTOR - Aggregated Computational Toxicology Resource
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DOI:
10.1016/j.taap.2007.12.037
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发表时间:
2008-11-15
影响因子:
3.8
通讯作者:
Wolf, Maritja
Wolf, Maritja
中科院分区:
医学3区
文献类型:
--
作者:
Judson, Richard;Richard, Ann;Wolf, Maritja

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ACTOR(聚合计算毒理学资源)是一个数据库和一套软件应用程序,将环境化学品的许多类型和来源的数据集中到一个中心位置。目前,ACToR化学数据库包含来自150多个来源的化学结构、体外生物测定和体内毒理学测定的信息,包括美国环境保护署(EPA)、疾病控制中心(CDC)、美国食品和药物管理局(FDA)、美国国立卫生研究院(NIH)、国家机构、加拿大、欧洲和日本的相应政府机构,世界卫生组织(WHO)和非政府组织(NGO)。在EPA国家计算毒理学中心,ACToR帮助管理大型数据集,该数据集用于高通量环境化学品筛选和优先级排序计划,称为Toxcast(TM)。(C)爱思唯尔公司出版
ACTOR (Aggregated Computational Toxicology Resource) is a database and set of software applications that bring into one central location many types and sources of data on environmental chemicals. Currently, the ACToR chemical database contains information on chemical structure, in vitro bioassays and in vivo toxicology assays derived from more than 150 sources including the U.S. Environmental Protection Agency (EPA), Centers for Disease Control (CDC), U.S. Food and Drug Administration (FDA), National Institutes of Health (NIH), state agencies, corresponding government agencies in Canada, Europe and Japan, universities, the World Health Organization (WHO) and non-governmental organizations (NGOs). At the EPA National Center for Computational Toxicology, ACToR helps manage large data sets being used in a high-throughput environmental chemical screening and prioritization program called Toxcast (TM). (C) Published by Elsevier Inc.