CAT (FEL-D-I), DOG (CAN-F-I), AND COCKROACH ALLERGENS IN HOMES OF ASTHMATIC-CHILDREN FROM 3 CLIMATIC ZONES IN SWEDEN

CAT (FEL-D-I), DOG (CAN-F-I), AND COCKROACH ALLERGENS IN HOMES OF ASTHMATIC-CHILDREN FROM 3 CLIMATIC ZONES IN SWEDEN
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DOI:
10.1111/j.1398-9995.1994.tb01121.x
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发表时间:
1994-08-01
期刊:
影响因子:
12.4
通讯作者:
KJELLMAN, NIM
KJELLMAN, NIM
中科院分区:
医学1区
文献类型:
--
作者:
MUNIR, AKM;BJORKSTEN, B;KJELLMAN, NIM

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我们对瑞典三个不同气候区的123名哮喘儿童家中卧室、客厅、厨房和浴室的灰尘中猫(Fel d I)、狗(Can f I)和蟑螂(Per a I)过敏原的水平进行了调查。还测量了绝对室内湿度(AIH)、相对湿度(RH)、每小时换气次数(ach)以及空气中悬浮颗粒的数量。通过单克隆抗体酶联免疫吸附测定法(mab ELISA)确定了Fel d I、Can f I和Per a I过敏原的含量,并将其水平与各种环境因素相关联。主要的猫过敏原Fel d I在所有家庭中都被检测到,其浓度在每克细尘16纳克到28000纳克之间变化。狗过敏原Can f I在85%的家庭中被检测到,其水平在每克灰尘60纳克到866000纳克之间变化。蟑螂过敏原仅在一个家庭中被检测到(每克40纳克)。Fel d I和Can f I过敏原在地理上分布均匀。客厅灰尘中(含量)显著更高(P<......此处原文似乎不完整)
We have investigated the levels of cat (Fel d I), dog (Can f I), and cockroach (Per a I) allergens in dust from bedrooms, living rooms, kitchens, and bathrooms from 123 homes of asthmatic children in three zones of Sweden with varying climates. Absolute indoor humidity (AIH), relative humidity (RH), rate of ventilation in air changes per hour (ach), and number of airborne particles were also measured. Fel d I, Can f I, and Per a I allergen contents were determined by mab ELISA, and the levels were related to various environmental factors. The major cat allergen, Fel d I, was detected in all homes, and the concentrations varied between 16 ng and 28 000 ng/g fine dust. The dog allergen, Can f I, was detected in 85% of the homes, and the levels varied from 60 ng to 866 000 ng/g dust. Cockroach allergen was detected in only one home (40 ng/g). Fel d I and Can f I allergens were equally distributed geographically. Dust from living rooms contained significantly higher (P