Trajectories of quality of life and their association with anxiety in people with dementia in nursing homes: A 12-month follow-up study
Trajectories of quality of life and their association with anxiety in people with dementia in nursing homes: A 12-month follow-up study
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DOI：
10.1371/journal.pone.0203773
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发表时间：
2018-09-11
期刊：
影响因子：
3.7
通讯作者：
Kirkevold, Oyvind
中科院分区：
文献类型：
--
作者：
Goyal, Alka R.;Bergh, Sverre;Kirkevold, Oyvind
ObjectivesThis study aims to identify possible groups of people with dementia（PWD）in nursing homes with different trajectories of proxy-rated quality of life（QoL），and to explore how anxiety（沿着with other characteristics）was associated with these trajectories of QoL of PWD in nursing homes at a 12-month follow up.MethodsWe included 298 PWD aged 65 years and older from 17 Norwegian nursing homes.使用挪威版的痴呆焦虑量表（RAID-N）评估焦虑，定义为RAID-N评分≥ 12;通过晚期痴呆生活质量（QUID）评估代理评定的QoL。在基线和平均350天（SD 12.3）随访期后进行评估。一个增长混合模型确定了两个不同的轨迹的CRYPID分数。与logistic回归models.ResultsTrajectory组1（206名参与者）的参与者与焦虑的比例较低，更稳定，更好的生活质量，相比，轨迹组2（92名参与者）在12个月的随访。在多变量logistic回归分析中，日常生活活动的更严重的损害，沿着焦虑、抑郁、激越和基线时使用抗精神病药物，与属于轨迹组与代理评定的不良QoL.SignificancesThis研究表明，焦虑与12个月随访时PWD的代理评定的不良QoL相关。应努力确定老年痴呆症疗养院居民的焦虑，以启动治疗。
ObjectivesThis study aimed to identify possible groups of people with dementia (PWD) in nursing homes with different trajectories of proxy-rated quality of life (QoL), and to explore how anxiety (along with other characteristics) was associated with these trajectories of QoL of PWD in nursing homes at a 12-month follow-up.MethodsWe included 298 PWD aged 65 years and older from 17 Norwegian nursing homes. The Norwegian version of the Rating Anxiety in Dementia scale (RAID-N) was used to assess anxiety, defined as RAID-N score >= 12; proxy-rated QoL was assessed by Quality of Life in Late-Stage Dementia (QUALID). The assessments were made at baseline and after a mean follow-up period of 350 days (SD 12.3). A growth mixture model identified two distinct trajectories of QUALID scores. Association between the QUALID score trajectories and demographic and clinical characteristics were analyzed with logistic regression models.ResultsTrajectory group 1 (206 participants) had a lower proportion of participants with anxiety, and a more stable and better QoL, compared to trajectory group 2 (92 participants) at a 12-month follow-up. In a multivariate logistic regression analysis, more severe impairment in activities of daily living, along with presence of anxiety, depression, agitation, and use of antipsychotics at baseline, were associated with belonging to the trajectory group with proxy-rated poor QoL.SignificancesThis study reveals that anxiety is associated with proxy-rated poor QoL of PWD at a 12-month follow-up. Efforts should be made to identify anxiety among nursing home residents with dementia to initiate treatment.