A Mobile DNP Polarizer for Clinical Applications

A Mobile DNP Polarizer for Clinical Applications
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适用于临床应用的移动 DNP 偏振器

DOI:
10.1007/s00723-008-0130-8
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发表时间:
2008
影响因子:
1
通讯作者:
D. Hinderberger
D. Hinderberger
中科院分区:
物理与天体物理4区
文献类型:
--
作者:
K. Münnemann;C. Bauer;J. Schmiedeskamp;H.W. Spiess;W.G. Schreiber;D. Hinderberger

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提出了一种基于Halbach磁体的移动的低成本动态核极化(DNP)超极化装置,并在室温下用三种不同的自由基溶解在甘油-水混合物中证明了其性能。DNP增强因子的三芳基甲基为基础的自由基,TEMPOL和一个自旋标记的氮氧自由基的测量作为微波功率的函数,和外推的最大增强因子进行了比较。自旋标记的双光子晶体显示出最好的DNP效率,观察到高达-50的1H DNP增强因子,预计最大增强因子为-80。结果表明,与新的移动的装置可靠的DNP实验可以进行合理的高1H-DNP增强。
A mobile and low-cost apparatus for dynamic nuclear polarization (DNP) hyperpolarization based on a Halbach magnet is presented and its performance is demonstrated at room temperature and with three different radical species dissolved in a glycerol-water mixture. DNP enhancement factors for a triarylmethyl-based radical, TEMPOL and a polyelectrolyte spin-labeled with nitroxide radicals are measured as a function of the microwave power, and the extrapolated maximum enhancement factors are compared. The spin-labeled polyelectrolyte shows the best DNP efficiency and1H DNP enhancement factors up to −50 were observed and a maximum enhancement factor of −80 was projected. The results demonstrate that with the new mobile apparatus reliable DNP experiments can be performed with reasonably high1H-DNP enhancements.
1H DNP 在 1.4 T 水中掺杂三芳基甲基自由基。
DOI: --
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