Evaluation of Choroidal Thickness in Patients with Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.
Evaluation of Choroidal Thickness in Patients with Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.
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DOI：
10.1155/2016/3545180
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发表时间：
2016
影响因子：
1.9
通讯作者：
Erdogan H
中科院分区：
文献类型：
--
作者：
Dursun A;Ozec AV;Dogan O;Dursun FG;Toker MI;Topalkara A;Arici MK;Erdogan H
目的。目的比较假剥脱（PEX）综合征和PEX青光眼与正常人的黄斑和乳头周围脉络膜厚度。材料与方法。本前瞻性研究纳入了30例PEX综合征患者的30只眼、28例PEX青光眼患者的28只眼和30例年龄匹配的健康受试者的30只眼。采用光谱域光学相干断层扫描测量黄斑和乳头周围的脉络膜厚度。结果。性别、年龄和轴长组间无显著差异（均p < 0.05）。PEX综合征及PEX型青光眼患者黄斑及乳头周围（除上象限）的脉络膜厚度平均值均低于对照组（均p < 0.05）。PEX青光眼组黄斑及乳头周围脉络膜厚度平均值低于PEX综合征组；然而，这种差异并不显著。结论。本研究结果显示，PEX综合征和PEX型青光眼患者黄斑和乳头周围脉络膜厚度减少。脉络膜在PEX综合征患者青光眼损害发展中的作用尚不清楚。
Purpose. To compare the macular and peripapillary choroidal thickness in eyes with pseudoexfoliation (PEX) syndrome and PEX glaucoma with the normal eyes of healthy controls. Materials and Methods. In this prospective study, 30 eyes of 30 patients with PEX syndrome, 28 eyes of 28 patients with PEX glaucoma, and 30 eyes of 30 age-matched healthy subjects were enrolled. Choroidal thicknesses in the macular and peripapillary areas were measured by using spectral domain optical coherence tomography. Results. Gender, age, and axial length did not significantly differ between the groups (all, p > 0.05). The mean values of choroidal thickness in the macular and peripapillary areas (except the superior quadrant) in the patients with PEX syndrome and PEX glaucoma were lower compared with controls (all p < 0.05). The mean values of the macular and peripapillary choroidal thickness in the PEX glaucoma group were lower compared with PEX syndrome group; however this difference was not significant. Conclusions. The findings of this study revealed that macular and peripapillary choroidal thicknesses were decreased in PEX syndrome and PEX glaucoma cases. The role of choroid in the development of glaucomatous damage in patients with PEX syndrome remains unclear.