Canine cardiac mesothelioma with granular cell morphology
Canine cardiac mesothelioma with granular cell morphology
复制标题
DOI：
10.1354/vp.43-3-384
复制
发表时间：
2006-05-01
影响因子：
2.4
通讯作者：
Kirby, BM
中科院分区：
文献类型：
--
作者：
Brower, A;Herold, LV;Kirby, BM
心脏间皮瘤与颗粒细胞的特点被诊断为10岁的金毛猎犬提出心包和腹腔积液。根据大体、形态学和免疫组化特征进行诊断。肿瘤的免疫组化特征为全细胞角蛋白阳性，波形蛋白阳性，S-100阴性;大多数大体和形态特征与间皮瘤和颗粒细胞瘤一致。据作者所知，狗的原发性心脏间皮瘤或颗粒细胞瘤的预后尚不清楚。在开胸术、心包切除术和肿块切除术后4个月，这只犬存活，没有心包或腹腔积液的临床证据。我们描述了一个颗粒形态变异的心脏间皮瘤在狗。
Cardiac mesothelioma with granular cell features was diagnosed in a 10-year-old Golden Retriever presenting with pericardial and abdominal effusions. The diagnosis was based on gross, morphologic, and immunohistochemical features. The immunohistochemical profile of the neoplasm was pancytokeratin positive, vimentin positive, and S-100 negative; most gross and morphologic features were consistent with both mesothelioma and granular cell tumor. To the authors' knowledge, the prognosis for either primary cardiac mesothelioma or granular cell tumor in the dog is unknown. At 4 months after thoracotomy, pericardectomy, and mass excision, this dog was alive and without clinical evidence of pericardial or abdominal effusions. We describe a granular morphologic variant of cardiac mesothelioma in a dog.