Social stress and atherosclerosis in normocholesterolemic monkeys.
Social stress and atherosclerosis in normocholesterolemic monkeys.
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正常胆固醇血症猴子的社会压力和动脉粥样硬化。
DOI：
10.1126/science.6836311
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Miller,EW
中科院分区：
文献类型：
--
作者：
Kaplan,JR;Manuck,SB;Clarkson,TB;Lusso,FM;Taub,DM;Miller,EW
社会压力的成年雄性食蟹猴（Macaca fascicularis）喂食低脂肪，低胆固醇饮食发展更广泛的冠状动脉粥样硬化比无压力的控制。各组在血脂、血压、血糖或体重方面没有差异。这些结果表明，在没有血脂升高的情况下，心理社会因素可能会影响动脉粥样硬化的形成。因此，社会心理因素可能有助于解释低血脂或正常血脂以及其他“传统”危险因素正常值的人群中冠状动脉疾病（偶尔严重）的存在。
Socially stressed adult male cynomolgus monkeys (Macaca fascicularis) fed a low fat, low cholesterol diet developed more extensive coronary artery atherosclerosis than unstressed controls. Groups did not differ in serum lipids, blood pressure, serum glucose, or ponderosity. These results suggest that psychosocial factors may influence atherogenesis in the absence of elevated serum lipids. Psychosocial factors thus may help explain the presence of coronary artery disease (occasionally severe) in people with low or normal serum lipids and normal values for the other "traditional" risk factors.