A small microbial genome:: The end of a long symbiotic relationship?

A small microbial genome:: The end of a long symbiotic relationship?
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DOI:
10.1126/science.1130441
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发表时间:
2006-10-13
期刊:
影响因子:
56.9
通讯作者:
Latorre, Amparo
Latorre, Amparo
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Perez-Brocal, Vicente;Gil, Rosario;Latorre, Amparo

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胞内细菌的特征是基因组减少。422,434碱基对的Buchnera aphidicola BCc基因组,蚜虫Cinara cedri的主要内共生体,类似于比先前测序的B小200个酶。蚜虫基因组B。蚜虫BCc丧失了大部分代谢功能,包括合成必需氨基酸色氨酸和核黄素的能力。此外,大多数保留的基因正在迅速进化。可能吧,B。Aphidicola BCc正在失去其共生能力,并被高度丰富的共存的次级共生体补充(并可能被取代)。
Intracellular bacteria are characterized by genome reduction. The 422,434 - base pair genome of Buchnera aphidicola BCc, primary endosymbiont of the aphid Cinara cedri, is similar to 200 kilobases smaller than the previously sequenced B. aphidicola genomes. B. aphidicola BCc has lost most metabolic functions, including the ability to synthesize the essential amino acid tryptophan and riboflavin. In addition, most retained genes are evolving rapidly. Possibly, B. aphidicola BCc is losing its symbiotic capacity and is being complemented ( and might be replaced) by the highly abundant coexisting secondary symbiont.