The Universal Medical Language System and the Gene Ontology: Some Critical Reflections
The Universal Medical Language System and the Gene Ontology: Some Critical Reflections
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通用医学语言系统和基因本体论：一些批判性的思考
DOI：
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发表时间：
2003
期刊：
影响因子：
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通讯作者：
Barry Smith
中科院分区：
文献类型：
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作者：
Anand Kumar;Barry Smith
统一医学语言系统和基因本体是生物医学领域使用最广泛的术语资源之一。然而，当我们根据构建良好的本体论的简单原则来评估它们时，我们发现了许多特征性的不足之处。采用颗粒划分理论，这是一种理解本体论以及本体论与现实实例之间的关系的新方法，我们提供了该理论在高血压病理生理学背景下的一个例子的应用。本练习旨在演示如何通过考虑本体论原理来创建更现实的生物医学本体论，这也将在相关软件应用程序的效率和稳健性方面带来优势。
The Unified Medical Language System and the Gene Ontology are among the most widely used terminology resources in the biomedical domain. However, when we evaluate them in the light of simple principles for well-constructed ontologies we find a number of characteristic inadequacies. Employing the theory of granular partitions, a new approach to the understanding of ontologies and of the relationships ontologies bear to instances in reality, we provide an application of this theory in relation to an example drawn from the context of the pathophysiology of hypertension. This exercise is designed to demonstrate how, by taking ontological principles into account we can create more realistic biomedical ontologies which will also bring advantages in terms of efficiency and robustness of associated software applications.