Treatment of central post-stroke pain with oral ketamine
Treatment of central post-stroke pain with oral ketamine
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DOI：
10.1016/s0304-3959(00)00488-7
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发表时间：
2001-05-01
期刊：
影响因子：
7.4
通讯作者：
Lamer, TJ
中科院分区：
文献类型：
--
作者：
Vick, PG;Lamer, TJ
口服氯胺酮成功治疗68岁女性卒中后中枢性疼痛的病例报告。患者的疼痛是传统疼痛治疗难治性的，她有持续的右半侧躯体神经性疼痛伴异常性疼痛和痛觉过敏。一项静脉注射氯胺酮的试验。随后口服氯胺酮，滴定至50mg，每日三次，有利于减轻异常性疼痛和痛觉过敏，以及改善功能能力。已知的副作用，包括烦躁不安，幻觉，偏执的感觉与苯二氮卓类药物减弱。(C)2001爱思唯尔科学爱尔兰有限公司保留所有权利。
Case report of 68 year old female with central post-stroke pain successfully treated with oral ketamine. The patients pain was refractory to conventional pain treatments and she had persistent right hemi-body neuropathic pain with allodynia and hyperalgesia. An intravenous ketamine trial. followed by oral ketamine with titration to 50mg three times a day was beneficial in decreasing allodynia and hyperalgesia, as well as improving functional capabilities. Known side effects including dysphoria, hallucinations, and paranoid feelings were attenuated with benzodiazepines. (C) 2001 Elsevier Science Ireland Ltd All rights reserved.