SWELLING OF THE CORNEA INVIVO AFTER THE DESTRUCTION OF ITS LIMITING LAYERS
SWELLING OF THE CORNEA INVIVO AFTER THE DESTRUCTION OF ITS LIMITING LAYERS
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DOI：
10.1136/bjo.35.12.791
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发表时间：
1951-01-01
影响因子：
4.1
通讯作者：
GIARDINI, AA
中科院分区：
文献类型：
--
作者：
MAURICE, DM;GIARDINI, AA
结果16只动物角膜平均厚度为0.375mm。（平均值的标准误差为0.01 mm。）假设平均折射率为1.38。在任何动物中，这在水平子午线的大部分周围都是相当恒定的。该数字优选为较低的值（0.33 mm）。Maurice（1951）根据某些角膜的面积、重量和密度得出。去除上皮后的变化。在图1中，曲线A显示了在去除上皮后的最初几个小时内，来自11只动物的17个角膜的光学厚度的平均（中值）变化。相应于上皮的厚度，立即下降约8%。在此之后，有一个快速膨胀的时期，最初约为每分钟总厚度的-1%，但一小时后，增加速度明显降低。在研究的每只动物中，肿胀曲线并没有稳定上升;有时，没有明显的原因，快速肿胀的时期与厚度保持不变或缓慢增加的长达1小时的时期交替出现。个别曲线所显示的极限范围如图所示。1箭
RESULTS The average thickness of the cornea in sixteen animals was 0.375 mm.(standard error of the mean 0.01 mm.) assuming an averagerefractive index of 1.38. In any animal this was appreciably constant round the greater part of the horizontal meridian. This figure is to be preferred to a lower value (0.33 mm.) derived from the area, weight, and density of some corneae by Maurice (1951).CHANGES AFTER REMOVAL OF THE EPITHELIUM.-In Fig. 1, Curve A shows the average (median) change in the optical thickness of seventeen corneae from eleven animals in the first few hours after the removal of the epithelium. Thereis an immediate drop of roughly 8 per cent. corresponding to the thickness of the epithelium. After this there is a period of rapid swelling, which is initially about-1 per cent. of its total thickness per minute, but after one hour the rate of increase becomes markedly lower. The swelling curve did not risesteadily in the case of every animal studied; sometimes, for no evident reason, periods of rapid swelling alternated with periods of as long as one hour when the thickness remained constant or increased slowly. The extreme ranges exhibited by the individualcurves are indicated inFig. 1 by arrows.