Hypercalcaemia following the use of antibiotic-eluting absorbable calcium sulphate beads in revision arthroplasty for infection
Hypercalcaemia following the use of antibiotic-eluting absorbable calcium sulphate beads in revision arthroplasty for infection
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DOI：
10.1302/0301-620x.97b9.34532
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发表时间：
2015-09-01
影响因子：
4.6
通讯作者：
Haddad, F. S.
中科院分区：
文献类型：
--
作者：
Kallala, R.;Haddad, F. S.
假体周围关节感染（PJI）是患者的一种毁灭性并发症，导致医疗保健提供者和患者的护理成本大幅增加。2013年，英格兰、威尔士和北方爱尔兰记录了超过15500例髋关节和膝关节翻修手术，其中感染占髋关节翻修手术的13%和膝关节翻修手术的23%。我们报告了15例使用抗生素洗脱可吸收硫酸钙珠的经验（8名男性和7名女性，平均年龄64.8岁; 41 - 83岁），作为关节翻修术中PJI治疗方案的一部分。平均随访时间为16个月（12 - 22）。我们报告的结果和并发症，强调高钙血症的风险发生在三个patients.We建议，血清钙水平，定期寻求可吸收硫酸钙珠植入骨科手术后。
Periprosthetic joint infection (PJI) is a devastating complication for patients and results in greatly increased costs of care for both healthcare providers and patients. More than 15 500 revision hip and knee procedures were recorded in England, Wales and Northern Ireland in 2013, with infection accounting for 13% of revision hip and 23% of revision knee procedures.We report our experience of using antibiotic eluting absorbable calcium sulphate beads in 15 patients (eight men and seven women with a mean age of 64.8 years; 41 to 83) as part of a treatment protocol for PJI in revision arthroplasty.The mean follow-up was 16 months (12 to 22). We report the outcomes and complications, highlighting the risk of hypercalcaemia which occurred in three patients.We recommend that serum levels of calcium be routinely sought following the implantation of absorbable calcium sulphate beads in orthopaedic surgery.