The importance of non-exercise physical activity for cardiovascular health and longevity
The importance of non-exercise physical activity for cardiovascular health and longevity
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DOI：
10.1136/bjsports-2012-092038
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发表时间：
2014-02-01
影响因子：
18.4
通讯作者：
Hellenius, Mai-Lis
中科院分区：
文献类型：
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作者：
Ekblom-Bak, Elin;Ekblom, Bjorn;Hellenius, Mai-Lis
在所有社会中，久坐时间都在增加，导致日常生活中非运动身体活动（NEPA）有限。低NEPA对心血管健康和寿命的重要性是有限的，特别是在老年人中。目的探讨NEPA与基线时心血管健康、12.5年后首次心血管疾病（CVD）事件风险和总死亡率之间的关系。研究设计队列研究。材料和方法斯德哥尔摩县每三分之一的60岁男女被邀请参加健康筛查研究；4232人参与（回复率78%）。在基线时，通过自我管理的问卷评估NEPA和运动习惯，并通过体格检查和实验室测试确定心血管健康状况。参与者平均随访12.5年，以评估心血管疾病事件和死亡率。结果在基线时，与低NEPA相比，高NEPA与更理想的腰围、高密度脂蛋白胆固醇和甘油三酯有关，与男性更低的胰岛素、葡萄糖和纤维蛋白原水平有关。此外，在不运动和经常运动的个体中，NEPA水平较高的个体代谢综合征的发生率明显较低。此外，报告较高的NEPA水平与较低的NEPA水平相比，与较低的首次心血管事件风险（HR=0.73; 95% CI 0.57至0.94）和较低的全因死亡率（0.70；0.53至0.98）相关。结论：无论是否有规律地锻炼，普遍活跃的日常生活与老年人的心血管健康和寿命有关。
Background Sedentary time is increasing in all societies and results in limited non-exercise physical activity (NEPA) of daily life. The importance of low NEPA for cardiovascular health and longevity is limited, especially in elderly.Aim To examine the association between NEPA and cardiovascular health at baseline as well as the risk of a first cardiovascular disease (CVD) event and total mortality after 12.5 years.Study design Cohort study.Material and methods Every third 60-year-old man and woman in Stockholm County was invited to a health screening study; 4232 individuals participated (78% response rate). At baseline, NEPA and exercise habits were assessed from a self-administrated questionnaire and cardiovascular health was established through physical examinations and laboratory tests. The participants were followed for an average of 12.5 years for the assessment of CVD events and mortality.Results At baseline, high NEPA was, regardless of regular exercise and compared with low NEPA, associated with more preferable waist circumference, high-density lipoprotein cholesterol and triglycerides in both sexes and with lower insulin, glucose and fibrinogen levels in men. Moreover, the occurrence of the metabolic syndrome was significantly lower in those with higher NEPA levels in non-exercising and regularly exercising individuals. Furthermore, reporting a high NEPA level, compared with low, was associated with a lower risk of a first CVD event (HR=0.73; 95% CI 0.57 to 0.94) and lower all-cause mortality (0.70; 0.53 to 0.98).Conclusions A generally active daily life was, regardless of exercising regularly or not, associated with cardiovascular health and longevity in older adults.