Doppler measurement of myocardial thickening with a single epicardial transducer.
Doppler measurement of myocardial thickening with a single epicardial transducer.
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使用单个心外膜传感器对心肌增厚进行多普勒测量。
DOI：
10.1152/ajpheart.1983.245.6.h1066
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Entman,ML
中科院分区：
文献类型：
--
作者：
Hartley,CJ;Latson,LA;Michael,LH;Seidel,CL;Lewis,RM;Entman,ML
为了消除在测量局部左心室(LV)功能时对心肌内换能器的需求，我们开发了一种利用单个心外膜换能器的脉冲多普勒技术。通过对穿过选定深度处的样本体积的心肌层的速度进行数字积分来评估室壁增厚。然后，增厚分数(Tf)可以通过将收缩期漂移除以样本体积深度来估计。在3只急性心肌梗死犬中，将直径4 mm的心外膜多普勒探头置于直径2 mm的心内膜晶体上，通过室壁穿透，比较了多普勒法和传递时间法。当样本体积小于最小左心室厚度1 mm时，多普勒法和传递时间法同时测量的Tf在对照、缺血、容量超载、休克和缺氧时具有良好的一致性(r=0.95)。在28只长期使用仪器的仔猪中，用多普勒换能器获得的信号周期比用渡越时间段长度晶体获得的信号周期长。我们的结论是，多普勒技术提供了高保真的室壁增厚波形和良好的Tf估计，对脑室的干扰最小，该技术适用于急性期和慢性期的动物。
To eliminate the need for intramyocardial transducers in measuring regional left ventricular (LV) function we have developed a pulsed Doppler technique utilizing a single epicardial transducer. Wall thickening is evaluated by digitally integrating the velocity of myocardial layers passing through the sample volume located at a selected depth. Thickening fraction (TF) can then be estimated by dividing the systolic excursion by the sample volume depth. The Doppler method was compared with the transit-time method in three acute dogs by placing the 4-mm-diameter epicardial Doppler transducer over a 2-mm-diameter endocardial crystal tunneled through the LV wall. With the sample volume set to 1 mm less than the minimum LV thickness, simultaneous measurements of TF by the Doppler and transit-time methods showed good agreement (r = 0.95) during control, ischemia, volume overload, shock, and anoxia. In 28 chronically instrumented piglets signals were obtained for longer periods with Doppler transducers than with transit-time segment-length crystals. We conclude that the Doppler technique provides a high-fidelity wall thickening waveform and a good estimate of TF with minimal disturbance to the ventricle and that the technique is suitable for use in both acute and chronically instrumented animals.