A convenient and eco-friendly cerium(III) chloride-catalysed synthesis of methoxime derivatives of aromatic aldehydes and ketones
A convenient and eco-friendly cerium(III) chloride-catalysed synthesis of methoxime derivatives of aromatic aldehydes and ketones
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DOI：
10.1098/rsos.180279
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发表时间：
2018-05-01
影响因子：
3.5
通讯作者：
Bracca, Andrea B. J.
中科院分区：
文献类型：
--
作者：
Cortes, Ivan;Kaufman, Teodoro S.;Bracca, Andrea B. J.
报道了利用CeCl3中心点7H(2)O作为高效环保的促进剂，方便地合成由芳香醛和酮类化合物衍生的甲氧基肟。转化需要在50℃的EtOH中使用等摩尔量的MeONH2中心点HCl和NaOAc，并且不需要特别注意氧气的存在。研究了转化的范围和局限性，提出了反应机理。
The use of CeCl3 center dot 7H(2)O as an efficient and eco-friendly promoter for the convenient synthesis of methoximes derived from aromatic aldehydes and ketones, is reported. The transformations entail the use of equimolar amounts of MeONH2 center dot HCl and NaOAc in EtOH at 50 degrees C, and no special precautions are needed with regard to the presence of oxygen. The scope and limitations of the transformation were studied and a reaction mechanism was proposed.