ISOLATION OF SIDE-CHAIN SULFATED SAXITOXIN ANALOGS - THEIR SIGNIFICANCE IN INTERPRETATION OF THE MECHANISM OF ACTION
ISOLATION OF SIDE-CHAIN SULFATED SAXITOXIN ANALOGS - THEIR SIGNIFICANCE IN INTERPRETATION OF THE MECHANISM OF ACTION
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DOI：
10.1016/0040-4020(84)85059-0
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发表时间：
1984-01-01
期刊：
影响因子：
2.1
通讯作者：
OSHIMA, Y
中科院分区：
文献类型：
--
作者：
SHIMIZU, Y;KOBAYASHI, M;OSHIMA, Y
一种新发现的毒素-和两种以前报道的来自鬼鱼的毒素-V和-VI，与氨基甲酰N-硫酸盐发生了结合。这些衍生物的低毒性质似乎支持了毒素在可兴奋的膜表面相互作用的假设。
A newly discovered toxin, gonyautoxin-VIII, and 2 previously reported toxins from Gonyaulax, gonyautoxin-V and -VI, had carbamoyl N-sulfate conjugation. The low toxic nature of the derivatives seemed to support the hypothesis that the toxins interacted on the surface of excitable membranes.