Pinnaic acid and tauropinnaic acid: Two novel fatty acids composing a 6-Azaspiro[4.5]decane unit from the Okinawan bivalve Pinna muricata

Pinnaic acid and tauropinnaic acid: Two novel fatty acids composing a 6-Azaspiro[4.5]decane unit from the Okinawan bivalve Pinna muricata
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DOI:
10.1016/0040-4039(96)00704-6
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发表时间:
1996-05-27
影响因子:
1.8
通讯作者:
Uemura, D
Uemura, D
中科院分区:
化学4区
文献类型:
--
作者:
Chou, T;Kuramoto, M;Uemura, D

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从冲绳双壳类海产品Pinna muricata中分离得到两种具有cPLA(2)抑制活性的新型脂肪酸:羽酸(pinnaic acid)和牛磺羽酸(tauro-pinnaic acid)。它们的结构,包括C5,C9,C13和C14的相对立体化学,通过广泛的2D NMR光谱分析进行了鉴定。版权所有(C)1996 Elsevier Science Ltd
Two novel fatty acids with cPLA(2) inhibitory activity, pinnaic acid and tauro-pinnaic acid, were isolated from the Okinawan bivalve Pinna muricata. Their structures, including the relative stereochemistry at C5, C9, C13 and C14, were elucidated by extensive 2D NMR spectroscopic analysis. Copyright (C) 1996 Elsevier Science Ltd