Evaluation and Management of Well-Appearing Febrile Infants 8 to 60 Days Old
Evaluation and Management of Well-Appearing Febrile Infants 8 to 60 Days Old
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DOI：
10.1542/peds.2021-052228
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发表时间：
2021-08-01
期刊：
影响因子：
8
通讯作者：
Woods, Charles R., Jr.
中科院分区：
文献类型：
--
作者：
Pantell, Robert H.;Roberts, Kenneth B.;Woods, Charles R., Jr.
本指南涉及对外观良好、年龄 8 至 60 天、发烧 >= 38.0 摄氏度的足月婴儿的评估和管理。注明了排除情况。经过医疗保健研究和质量局委托进行循证审查、对文献进行额外广泛且持续的审查以及积极调查人员提供的已发表的同行评审研究的补充数据，得出了 21 项关键行动声明。对于每个关键行动声明，对证据质量和利弊关系进行评估和分级，以确定建议的强度。在适当的情况下，应将父母的价值观和偏好纳入共同决策的一部分。对于诊断测试，委员会试图制定测试所需的数据，对于抗菌药物管理，委员会提供了治疗所需的数据。三种算法总结了针对 8 至 21 天、22 至 28 天和 29 至 60 天婴儿的建议。本指南中的建议并不表明唯一的治疗方案或作为医疗护理的标准。考虑到个人情况，可能会有适当的变化。
This guideline addresses the evaluation and management of well-appearing, term infants, 8 to 60 days of age, with fever >= 38.0 degrees C. Exclusions are noted. After a commissioned evidence-based review by the Agency for Healthcare Research and Quality, an additional extensive and ongoing review of the literature, and supplemental data from published, peer-reviewed studies provided by active investigators, 21 key action statements were derived. For each key action statement, the quality of evidence and benefit-harm relationship were assessed and graded to determine the strength of recommendations. When appropriate, parents' values and preferences should be incorporated as part of shared decision-making. For diagnostic testing, the committee has attempted to develop numbers needed to test, and for antimicrobial administration, the committee provided numbers needed to treat. Three algorithms summarize the recommendations for infants 8 to 21 days of age, 22 to 28 days of age, and 29 to 60 days of age. The recommendations in this guideline do not indicate an exclusive course of treatment or serve as a standard of medical care. Variations, taking into account individual circumstances, may be appropriate.