Digital breast tomosynthesis: Initial experience in 98 women with abnormal digital screening mammography
Digital breast tomosynthesis: Initial experience in 98 women with abnormal digital screening mammography
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DOI：
10.2214/ajr.07.2231
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发表时间：
2007-09-01
影响因子：
5
通讯作者：
Nagy, Helene M.
中科院分区：
文献类型：
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作者：
Poplack, Steven P.;Tosteson, Tor D.;Nagy, Helene M.
客观的。我们研究的目的是比较断层合成与传统乳房X线摄影的图像质量，并估计当除了乳房X线摄影之外还使用断层合成时筛查的召回率。 材料和方法。依次招募乳房X光检查筛查异常的女性。同意的女性接受了受影响乳房的断层合成，与诊断性乳房X光检查获得的视图相对应。研究放射科医生将断层合成与诊断胶片屏幕乳房X光检查的图像质量（包括病变明显性和特征分析）进行了比较，并评估了将断层合成添加到数字筛选乳房X光检查中时的回忆需求。当断层合成没有显示相应的异常或允许明确的良性病变特征时，筛选召回被认为是不必要的。 Fisher 精确检验用于确定等效性和回忆状态与乳房 X 光检查发现类型的关联。结果。对 98 名女性进行了 99 次数字筛选召回。 89% (88/99) 的断层合成图像质量与诊断性乳房 X 线摄影相当 (n = 51) 或优于 (n = 37)。结果类型与等效性显着相关（p < 0.001）。当数字筛查乳房X光检查辅以断层合成时，大约有一半的结果（52/99 (52%)）不会被回忆起来。当调整混杂条件时，召回率降低了 40% (37/92)。召回的可能性还取决于发现类型 (p = 0.004)。结论。主观上，断层合成在诊断环境中具有与胶片屏幕乳房X线照相相当或更好的图像质量，并且当与数字筛查乳房X线照相辅助使用时，它有可能降低召回率。
OBJECTIVE. The purpose of our study was to compare the image quality of tomosynthesis with that of conventional mammography and to estimate the recall rate of screening when tomosynthesis is used in addition to mammography.MATERIALS AND METHODS. Women with an abnormal screening mammography were recruited sequentially. Consenting women underwent tomosynthesis of the affected breast corresponding to the views obtained with diagnostic mammography. The study radiologist compared the image quality, including lesion conspicuity and feature analysis, of tomosynthesis with diagnostic film-screen mammography and assessed the need for recall when tomosynthesis was added to digital screening mammography. Screening recalls were considered unnecessary when tomosynthesis did not show a corresponding abnormality or allowed definitely benign lesion characterization. Fisher's exact test was used to determine the association of equivalence and recall status with mammographic finding type.RESULTS. There were 99 digital screening recalls in 98 women. The image quality of tomosynthesis was equivalent (n = 51) or superior (n = 37) to diagnostic mammography in 89% (88/99). Finding type was significantly (p < 0.001) associated with equivalence. Approximately half-52/99 (52%)-of the findings would not have been recalled when digital screening mammography was supplemented with tomosynthesis. When adjusting for confounding conditions, the recall reduction was 40% (37/92). The likelihood of recall was also dependent on finding type (p = 0.004).CONCLUSION. Subjectively, tomosynthesis has comparable or superior image quality to that of film-screen mammography in the diagnostic setting, and it has the potential to decrease the recall rate when used adjunctively with digital screening mammography.