Chemical imaging with Fourier transform coherent anti-Stokes Raman scattering microscopy
Chemical imaging with Fourier transform coherent anti-Stokes Raman scattering microscopy
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DOI：
10.1364/ao.47.005790
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发表时间：
2008-11-01
期刊：
影响因子：
1.9
通讯作者：
Ogilvie, Jennifer P.
中科院分区：
文献类型：
--
作者：
Cui, Meng;Skodack, Joshua;Ogilvie, Jennifer P.
我们报道了用相干傅里叶变换进行化学成像。反斯托克斯拉曼散射（FTCARS）显微镜。加入被动相位稳定的局部场来放大微弱的FTCARS信号，我们还演示了干涉式FTCARS显微镜，允许降低入射功率用于成像。我们讨论了信噪比考虑和必要的条件，以有效地抑制背景噪声，允许FTCARS显微镜，是由检测器的弹射噪声的限制。我们还讨论了时域相干反斯托克斯拉曼散射（CARS）方法和频域相干反斯托克斯拉曼散射（CARS）方法的信噪比差异。(C) 2008美国光学学会
We report chemical imaging using Fourier transform coherent. anti-Stokes Raman scattering (FTCARS) microscopy. Adding a passively phase-stable local field to amplify the weak FTCARS signal, we also demonstrate interferometric FTCARS microscopy, permitting reduced incident power to be used for imaging. We discuss signal-to-noise considerations and the conditions necessary to effectively suppress background noise, allowing FTCARS microscopy that is limited by the shot noise of the detector. We also discuss differences between the signal-to-noise obtainable by time and frequency domain coherent anti-Stokes Raman scattering (CARS) methods. (C) 2008 Optical Society of America