Orbital involvement with desmoplastic melanoma.
Orbital involvement with desmoplastic melanoma.
复制标题
眼眶受累促纤维增生性黑色素瘤。
DOI：
10.1136/bjo.71.4.279
复制
发表时间：
1987
影响因子：
4.1
通讯作者：
J. Augsburger
中科院分区：
文献类型：
--
作者：
J. Shields;D. Elder;V. Arbizo;T. Hedges;J. Augsburger
一位79岁的女性在切除鼻侧皮肤黑色素瘤后五年半出现眼眶肿块。最初的眼眶活检组织病理学解释为恶性纤维组织细胞瘤，但特殊染色和电子显微镜显示它是一个促结缔组织增生性恶性黑色素瘤，显然是从以前的皮肤病变扩散到眼眶的亲神经机制。眼眶内促结缔组织增生性嗜神经性黑色素瘤的发生以前没有被认识到。本文对这种罕见类型的黑色素瘤的临床和病理诊断中存在的问题进行了讨论。
A 79-year-old woman developed an orbital mass five and a half years after excision of a cutaneous melanoma from the side of the nose. The initial orbital biopsy was interpreted histopathologically as a malignant fibrous histiocytoma, but special stains and electron microscopy showed it to be a desmoplastic malignant melanoma which had apparently spread to the orbit from the prior skin lesion by neurotropic mechanisms. The occurrence of a desmoplastic neurotropic melanoma in the orbit has not been previously recognised. The problems in the clinical and pathological diagnosis of this rare type of melanoma are discussed.