Position of branch points in replicating λ DNA

Position of branch points in replicating λ DNA
复制标题

复制 λ DNA 时分支点的位置

DOI:
10.1016/0022-2836(70)90270-6
复制
发表时间:
1970
影响因子:
5.6
通讯作者:
R. Inman
R. Inman
中科院分区:
生物学2区
文献类型:
--
作者:
M. Schnös;R. Inman

文献摘要

被引文献

相似文献

Ogawa,Tomizawa & Fuke(1968)最近的实验表明,有可能分离出具有环状结构但在两个分支点之间延伸有额外长度的DNA的细胞内λ DNA。人们试图绘制这些分支点相对于成熟λ噬菌体DNA分子末端的环状结构上的点的位置,如果环状分支分子确实代表复制DNA,那么就可以得出关于复制起点和方向的某些结论。
Recent experiments by Ogawa, Tomizawa & Fuke (1968) have shown that it is possible to isolate intracellular λ DNA having a circular structure but with an extra length of DNA extending between two branch points. An attempt has been made to map the position of these branch points with respect to the point on the circular structure corresponding to the ends of the mature λ phage DNA molecule.If the circular branched molecules do, in fact, represent replicating DNA, then certain conclusions may be drawn concerning the starting point and direction of replication.