Pseudotumor cerebri and optic nerve sheath decompression
Pseudotumor cerebri and optic nerve sheath decompression
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DOI：
10.1016/s0161-6420(00)00340-7
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发表时间：
2000-10-01
期刊：
影响因子：
13.7
通讯作者：
Farris, BK
中科院分区：
文献类型：
--
作者：
Banta, JT;Farris, BK
目的：探讨视神经鞘减压术对大量经药物治疗后视力丧失的假性脑瘤患者的疗效和安全性，并在此基础上提出一种治疗方法。设计：回顾性、非比较性、干预性病例系列。研究对象：86例假性脑瘤患者158只眼。干预：视神经鞘减压。主要观察指标：视力、视野、手术并发症。结果：假性脑瘤视神经鞘减压术后，158只眼中有148只（94%）视力稳定或改善，81只眼中有71只（88%）视野稳定或改善。86例患者中有39例出现手术并发症，大多数是短暂的和良性的。一例患者只有一只眼睛因手术并发症而出现永久性严重视力丧失。结论：在假性脑瘤伴进行性视力丧失的患者中，视神经鞘减压术是一种安全有效的稳定视力和视野的方法。眼科2000;107:1907-1912 (C) 2000由美国眼科学会。
Objective: To determine the efficacy and safety of optic nerve sheath decompression in a large population of patients with pseudotumor cerebri with visual loss despite medical treatment and to suggest a treatment algorithm on the basis of these data.Design: Retrospective, noncomparative, interventional case series.Participants: One hundred fifty-eight eyes in 86 patients with pseudotumor cerebri.Intervention: Optic nerve sheath decompression.Main Outcome Measures: Visual acuity, visual fields, and surgical complications.Results: After optic nerve sheath decompression for pseudotumor cerebri, visual acuity stabilized or improved in 148 of 158 (94%) eyes, and visual fields stabilized or improved in 71 of 81 (88%) eyes. Surgical complications, most of which were transient and benign, were seen in 39 of 86 patients. Only one eye in one patient had permanent severe visual loss secondary to an operative complication.Conclusions: in patients with pseudotumor cerebri with progressive visual loss despite maximum medical therapy, optic nerve sheath decompression is a safe and effective means of stabilizing visual acuity and the visual fields of those tested. Ophthalmology 2000;107:1907-1912 (C) 2000 by the American Academy of Ophthalmology.