The International Human Epigenome Consortium Data Portal
The International Human Epigenome Consortium Data Portal
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DOI：
10.1016/j.cels.2016.10.019
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发表时间：
2016-11-23
期刊：
影响因子：
9.3
通讯作者：
Bourque, Guillaume
中科院分区：
文献类型：
--
作者：
Bujold, David;Morais, David Anderson de Lima;Bourque, Guillaume
国际人类表观基因组联盟（IHEC）通过表征来自广泛组织和细胞类型的调节组、甲基化组和转录组来协调参考表观基因组图谱的产生。为了定义确保数据集兼容性的约定，并建立支持数据集成、分析和共享的基础设施，我们开发了IHEC数据门户（http：//epigenomesportal.ca/ihec）。该门户网站提供了超过7，000个参考表观基因组数据集的访问权限，这些数据集由超过600种组织生成，这些组织由七个国际财团提供：ENCODE、NIH Roadmap、CEEHRC、Blueprint、DEEP、AMED-CREST和KNIH。该门户网站通过促进表观基因组学数据的发现、可视化、分析、下载和共享来增强这些参考图谱的实用性。IHEC数据门户是浏览IHEC数据集的官方来源，代表了统一国际研究联盟产生的分布式数据的战略。
The International Human Epigenome Consortium (IHEC) coordinates the production of reference epigenome maps through the characterization of the regulome, methylome, and transcriptome from a wide range of tissues and cell types. To define conventions ensuring the compatibility of datasets and establish an infrastructure enabling data integration, analysis, and sharing, we developed the IHEC Data Portal (http://epigenomesportal.ca/ihec). The portal provides access to > 7,000 reference epigenomic datasets, generated from > 600 tissues, which have been contributed by seven international consortia: ENCODE, NIH Roadmap, CEEHRC, Blueprint, DEEP, AMED-CREST, and KNIH. The portal enhances the utility of these reference maps by facilitating the discovery, visualization, analysis, download, and sharing of epigenomics data. The IHEC Data Portal is the official source to navigate through IHEC datasets and represents a strategy for unifying the distributed data produced by international research consortia.