Deaths From Seasonal Influenza Among Pregnant Women in the United States, 1998-2005
Deaths From Seasonal Influenza Among Pregnant Women in the United States, 1998-2005
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DOI：
10.1097/aog.0b013e3181d99d85
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发表时间：
2010-05-01
影响因子：
7.2
通讯作者：
Jamieson, Denise J.
中科院分区：
文献类型：
--
作者：
Callaghan, William M.;Chu, Susan Y.;Jamieson, Denise J.
目的：估计妊娠相关的死亡率引起的季节性流感在美国与目前的2009年甲型H1N1流感pandemic.METHODS比较：妊娠相关的死亡被确定在美国疾病控制和预防中心（CDC）的妊娠死亡率监测系统（PMSS）数据库的1998年至2005年。PMSS收集所有50个州、哥伦比亚特区和纽约市提供的在怀孕期间或怀孕后1年内死亡的妇女的生命记录的去识别副本。在数据库中的记录广泛分类下的死亡，由于呼吸道感染进行了鉴定，相应的存档死亡证明书进行了单独审查，分类为肺炎或流感的死因。其中，78名妇女死于流感或肺炎;其中40人死于流感季节。近75%的死亡发生期间或2周内结束的pregnancy.CONCLUSION：平均而言，5个可能的流感相关的死亡孕妇之间的出现之前，每年报告的妊娠相关的死亡，由于目前的H1N1流感大流行相比，28个实验室确认，妊娠相关的死亡报告的前4个月的2009年大流行。这突出表明，这一大流行性流感病毒导致孕妇死亡率过高。（妇产科2010;115：919-23）
OBJECTIVE: To estimate pregnancy-related mortality caused by seasonal influenza in the United States for comparison with the current 2009 influenza A H1N1 pandemic.METHODS: Pregnancy-related deaths were identified in the U.S. Centers for Disease Control and Prevention's (CDC) Pregnancy Mortality Surveillance System (PMSS) database for the years 1998-2005. PMSS collects de-identified copies of vital records supplied by all 50 states, the District of Columbia, and New York City for women who died during or within 1 year after pregnancy. Records in the database broadly classified under deaths due to respiratory infections were identified, and the corresponding archived death certificates were individually reviewed to classify the cause of death as pneumonia or influenza.RESULTS: Between 1998 and 2005, 4,693 pregnancy-related deaths were reported to CDC. Of these, 78 women died from influenza or pneumonia; 40 of these deaths occurred during an influenza season. Nearly 75% of deaths occurred during or within 2 weeks of the end of the pregnancy.CONCLUSION: On average, five possible influenza-related deaths among pregnant women were reported per year before the emergence of pregnancy-related deaths due to the current H1N1 pandemic compared with the 28 laboratory-confirmed, pregnancy-related deaths reported for the first 4 months of the 2009 pandemic. This highlights the excess mortality among pregnant women resulting from this pandemic influenza virus. (Obstet Gynecol 2010;115:919-23)