Structure and urovirulence characteristics of the fecal Escherichia coli population among healthy women
Structure and urovirulence characteristics of the fecal Escherichia coli population among healthy women
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DOI：
10.1016/j.micinf.2008.12.002
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发表时间：
2009-02-01
影响因子：
5.8
通讯作者：
Andreu, Antonia
中科院分区：
文献类型：
--
作者：
Moreno, Eva;Johnson, James R.;Andreu, Antonia
粪便大肠杆菌种群结构可能影响肠外感染的发生和病因，但了解甚少。因此，粪便E.对来自39名健康妇女的大肠杆菌（每个受试者30个假定菌落）进行克隆特性、尿路感染相关毒力特征和系统发育背景的表征。120种独特的E.大肠杆菌克隆（平均每个样品3个）按系统发生群分布如下：A（33%）、D（31%）、B1（19%）和B2（17%）。然而，36%的女性携带>= 1个来自B2组的克隆，87%的女性携带来自B2和/或D组的克隆。在B2克隆中，90%来自少克隆粪便样品（
The fecal Escherichia coli population structure may influence the occurrence and etiology of extraintestinal infection, but is poorly understood. Accordingly, fecal E. coli from 39 healthy women (30 putative colonies per subject) were characterized for clonal identity, urinary tract infection-associated virulence traits, and phylogenetic background. The 120 unique E. coli clones (mean, three per sample) were distributed by phylogenetic group as follows: A (33%), D (31%), B1 (19%), and B2 (17%). However, 36% of women carried >= 1 clone from group B2, and 87% had clones from groups B2 and/or D. Of the B2 clones, 90% were from pauciclonal fecal samples (