Food Intake and the Risk of Endometrial Endometrioid Adenocarcinoma in Japanese Women
Food Intake and the Risk of Endometrial Endometrioid Adenocarcinoma in Japanese Women
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DOI：
10.1080/01635581.2013.818158
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发表时间：
2013-10-01
影响因子：
2.9
通讯作者：
Yaegashi, Nobuo
中科院分区：
文献类型：
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作者：
Takayama, Shin;Monma, Yasutake;Yaegashi, Nobuo
本研究通过对日本女性的病例对照研究，探讨了食物摄入与子宫内膜癌（仅限于子宫内膜样腺癌（EEA））之间的关系。对161例病例和380例对照者进行了人口统计、生活方式和食物频率问卷调查。采用logistic回归分析计算食物摄入量与EEA的比值比（OR）。调整假定的混杂因素后，蔬菜(优势比（OR) = 0.47, 95%可信区间(CI) = 0.26-0.83）、花生（OR = 0.48, CI = 0.27-0.86）、鱼（OR = 0.52, CI = 0.29-0.93）、煮鸡蛋（OR = 0.24, CI = 0.33-0.92）、方便面（OR = 1.94, CI = 1.12-3.34）、速食食品（OR = 2.21, CI = 1.31-3.74）和油炸食品（OR = 2.87, CI = 1.58-5.21）的高摄入量与EEA风险相关。与低摄入量相比，蔬菜（0.45,CI = 0.25-0.81）和鱼类（0.53,CI = 0.30-0.94）的高摄入量（g/1000千卡）也与EEA风险呈负相关。摄入较多的蔬菜、花生、鱼和煮鸡蛋与患EEA的风险降低有关，而方便面、速食食品和油炸食品与摄入较少的食物相比，患EAA的风险增加有关。
The present study examined the association between food intake and endometrial cancer restricted to endometrial endometrioid adenocarcinoma (EEA) using a case-control study in Japanese women. One hundred sixty-one cases and 380 controls who completed a questionnaire regarding demographic, lifestyle, and food frequency questionnaire were analyzed. Odds ratio (OR) between selected food intakes and EEA were calculated by logistic regression analysis. After adjustment putative confounding factors, the higher intakes of vegetables [odds ratio (OR) = 0.47, 95% confidence interval (CI) = 0.26-0.83], peanuts (OR = 0.48, CI = 0.27-0.86), fish (OR = 0.52, CI = 0.29-0.93), boiled egg (OR = 0.24, CI = 0.33-0.92), instant noodles (OR = 1.94, CI = 1.12-3.34), instant food items (OR = 2.21, CI = 1.31-3.74), and deep-fried foods (OR = 2.87, CI = 1.58-5.21) were associated with a risk for EEA. The inverse association with a risk of EEA was also seen in higher intakes (g/1000 kcal) for vegetables (0.45, CI = 0.25-0.81) and fish (0.53, CI = 0.30-0.94) as compare to lower intake. Higher intake of vegetables, peanuts, fish, and boiled egg was associated with a reduced risk for EEA, whereas instant noodles, instant food items, and deep-fried foods was associated with an increased risk for EAA as compared to lower levels of intake.