The promise of novel technology for the prevention of intravascular device-related bloodstream infection. II. Long-term devices
The promise of novel technology for the prevention of intravascular device-related bloodstream infection. II. Long-term devices
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DOI：
10.1086/340105
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发表时间：
2002-05-15
影响因子：
11.8
通讯作者：
Maki, DG
中科院分区：
文献类型：
--
作者：
Crnich, CJ;Maki, DG
血管内装置 (IVD) 广泛用于血管通路，但存在 IVD 相关血流感染 (BSI) 的巨大风险。基于我们对发病机制的理解而开发的新技术有望在护理人员日益短缺的时代大量减少 IVD 相关感染。长期 IVD（大多数持续时间大于或等于 10 天）的感染，包括带套囊和隧道式中心静脉导管 (CVC)、植入式皮下中心静脉端口和外周插入中心静脉导管 (PICC)，主要是由于进入导管毂和管腔的微生物造成的。前瞻性随机试验表明，新型固定装置和抗生素锁定解决方案可以降低 IVD 相关 BSI 的风险。未来的挑战将是确定新的预防技术，并开始更广泛地采用那些已被证明有效且具有成本效益的技术。
Intravascular devices (IVDs) are widely used for vascular access but are associated with a substantial risk of IVD-related bloodstream infection (BSI). The development of novel technologies based on our understanding of pathogenesis promises a quantum reduction in IVD-related infections in an era of growing nursing shortage. Infections of long-term IVDs (most are in place for greater than or equal to10 days), including cuffed and tunneled central venous catheters (CVCs), implanted subcutaneous central venous ports, and peripherally inserted central catheters (PICCs), are primarily due to microorganisms that gain access to the catheter hub and lumen. Novel securement devices and antibiotic lock solutions have been shown to reduce the risk of IVD-related BSI in prospective randomized trials. The challenge for the future will be to identify new preventative technologies and to begin to more-widely adapt those technologies that have already been shown to be efficacious and cost effective.